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Found 938 All Conditions trials
A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
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This study investigates a treatment for patients with acute myeloid leukemia (AML) who are not eligible for bone marrow transplantation. The purpose of the study is to evaluate the safety and tolerability of an investigational medication given as maintenance therapy. Patients in this study have AML, which is a type …
The overarching objective of this proposal is to determine if NGS technology is capable of detecting bacterial DNA in patients who sustained an open fracture and are undergoing the initial debridement. The central hypothesis is that NGS sampling will be able to more accurately, and reliably identify potential sources of …
Phase II and III: To compare time to DFS event (recurrence, second primary colorectal cancer or death) in ctDNA (+ve) cohort following resection of colon cancer treated with 5-FU (orcapecitabine) and oxaliplatin x 6 months or 5-FU, oxaliplatin and irinotecan x 6 months.
This study investigates the use of an investigational medication, a monoclonal antibody targeting Tumor Necrosis Factor Receptor 2 (TNFR2), in people with advanced malignancies. The purpose of the study is to evaluate the safety and tolerability of the investigational medication both alone and in combination with pembrolizumab, a type of …
The purpose of the Pancreatic Cancer Early Detection (PRECEDE) Consortium is to conduct research on multiple aspects of early detection and prevention of pancreatic ductal adenocarcinoma (PDAC) by establishing a multi-site cohort of individuals with family history of PDAC and/or individuals carrying pathogenic/likely pathogenic germline variants (PGVs) in genes linked …
The objective of this study is to obtain neural recordings from deep brain structures while performing simple intraoperative tasks in order to improve the understanding of temporal relationship of deep neural signals and the performance of simple psychomotor, cognitive, and/or executive tasks. The standard DBS surgery provides an opportunity to …
This study investigates the use of investigational medications following CAR T-cell therapy for individuals with relapsed or refractory large B-cell lymphoma and grade IIIB follicular lymphoma. The purpose of this study is to determine if additional treatment with investigational medications, after initial chemotherapy and CAR T-cell therapy, can better manage …
This study compares the impact of using a combination of drugs, ramucirumab and pembrolizumab, versus standard chemotherapy for treating advanced non-small cell lung cancer that is stage IV or recurrent. Ramucirumab blocks new blood vessel growth that tumors need, while pembrolizumab boosts the immune system to fight cancer. The trial …
This study will compare the good and bad effects of not giving regional radiotherapy versus using regional radiotherapy in patients with low risk breast cancer as indicated by Oncotype DX Recurrence Score. This is intended to help researchers discover if not giving regional radiotherapy will be as beneficial as using …
A Phase 2 study to evaluate the clinical activity, safety, and potentially predictive biomarker profile of ZN-c3 in subjects with High-Grade Serous Ovarian, Fallopian Tube, or Primary Peritoneal Cancer
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