Found 938 All Conditions trials
A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
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This study investigates the safety and tolerability of an investigational medication in patients with advanced solid tumors and lymphomas. The study is divided into two phases: Phase 1 focuses on finding the maximum tolerated dose of the investigational medication, while Phase 2 evaluates its antitumor activity across different types of …
This study investigates the safety and feasibility of using T-cell receptor engineered donor T-cells in patients undergoing allogeneic peripheral blood stem cell transplantation. The study focuses on patients with acute myeloid leukemia (AML), myelodysplastic syndromes (MDS), or acute lymphoblastic leukemia (ALL) who receive transplants from specific types of donors. The …
The primary aims of this trial are to determine (i) whether patients undergoing (a) major inpatient surgery, (b) minor inpatient surgery, or (c) outpatient surgery have a superior quality of recovery after INVA or TIVA and (ii) whether TIVA confers no more than a small (0.2%) increased risk of intraoperative …
This is a randomized, response-adaptive, duration/dose finding, comparative effectiveness clinical trial with blinded outcome assessment for post-cardiac arrest patients to characterize the duration response curve for hypothermia and determine in each of two populations: the shortest duration of cooling that provides the maximal treatment effect, and whether the duration-response implies …
This study investigates how genetic testing can guide cancer treatment choices for patients with advanced solid tumors. The purpose is to use the genetic information from patients' tumor cells to match them with investigational combination therapies that target specific genetic mutations. This approach aims to control tumor growth and improve …
This study investigates the effects of adding an investigational medication, a type of immunotherapy, to chemotherapy before surgery in patients with high-grade upper tract urothelial cancer. Immunotherapy uses substances to stimulate or support the immune system to fight cancer, while chemotherapy uses drugs to kill or slow the growth of …
This is a long-term follow up of participants enrolled in the CHAP trial during a 5-year window starting between 0-6 years until 5-10 years after their participation in the original CHAP trial. The goal is to determine whether treatment of mild CHTN in pregnancy influences maternal risk of cardiovascular disease …
The purpose of this study is to investigate prostate cancer in individuals who have a genetic risk for the disease. Prostate cancer is a common cancer in men, especially those with inherited genetic changes in certain genes like BRCA1, BRCA2, ATM, TP53, and HOXB13. These genetic changes can increase the …
This study investigates the safety and appropriate dosing of investigational cells in patients with T Cell Non-Hodgkin Lymphoma. The purpose of this study is to determine how well these cells can be tolerated by patients and to identify the best dose for future studies. The focus is on patients whose …
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