A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
This study is for patients who have NCFBE who also have comorbid P aeruginosa infections. This study is testing AP-PA02 as a possible treatment for these infections and consists of 5 phages. The study includes physicals, infectious disease blood tests, ECGs, HRCT, blood and urine safety labs and phage labs …
This is a prospective, single-arm, multi-center study on using the LimFlow System for creating an AV connection in the Below The Knee vascular system using an endovascular, minimally invasive approach to arterialize the pedal veins to treat chronic limb-threatening ischemia in subjects ineligible for conventional endovascular or surgical limb salvage …
The purpose of this research study is to determine the effectiveness and safety of envafolimab, an experimental drug that is not approved for use, when given alone or in combination with ipilimumab to stimulate your immune system to attack cancer cells. Eligible subjects are those with advanced or metastatic undifferentiated …
The primary purpose of this clinical research study is to test, for the first time in people, the safety (any good or bad effects) of the new experimental drug, CC-94676. We would like to rely on WCG IRB as the IRB of record for this study.
This Phase Ib/III study (CAPItello-292) aims to evaluate the efficacy, safety and the degree of added benefit of capivasertib combined with CDK4/6i (palbociclib, ribociclib or abemaciclib) and fulvestrant in participants with locally advanced (inoperable) or metastatic HR+/HER2- breast cancer. We would like to rely on WCG as the IRB of …
Compare the safety and efficacy of the Bare Temporary Spur Stent System in subjects with infrapopliteal critical limb ischemia (CLI) to a pre-defined performance goal based on standard percutaneous transluminal balloon angioplasty (PTA). Population: infrapopliteal CLI, Rutherford class 4-5, not considered amenable to conservative medical therapy and require endovascular intervention …
Assess magnitude of the baseline differences between participants with early Huntington's Disease & healthy participants with respect to measures of cognitive performance, evaluate effect of SAGE-718 on cognition & functioning outcomes in participants with HD & to evaluate safety & tolerability of SAGE718 in participants with HD, evaluate reliability & …
This is a multicenter, interventional and observational study to understand factors affecting the likelihood of transplantation in patients without a human leukocyte antigen (HLA) matched family donor and to compare outcomes associated with pursuing an HLA-identical unrelated versus other alternative donor graft sources. Subjects' outcomes will be assessed using several …
This study will evaluate the long-term (up to 15 years) safety and efficacy of CRISPR CAR cellular therapy for hematological and solid malignancies. We would like to rely on WCG as the local IRB of record for this study.
The purpose of this study is to better understand how blood vessel health impacts your thinking. The study is interested in the brains white matter, which is involved in the movement of messages and impulses throughout the brain. The study is run out of the University of California Davis and …