Found 930 All Conditions trials
A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
This is a Phase 1/2, multicenter, open label, study of DCC-3116 as monotherapy, and in combination with trametinib, binimetinib, or sotorasib in patients with advanced or metastatic solid tumors with RAS/MAPK pathway mutation. The study consists of 2 parts, a dose-escalation phase, and an expansion phase.
The goal of this is to evaluate the safety and effectiveness of the drug Ibudilast compared to placebo (an inactive pill) in reducing the number of drinking days and the amount of alcohol consumed by people who want to stop or reduce their drinking. Study duration 11 weeks and includes …
This phase III trial compares denosumab to placebo for the prevention of breast cancer in women with a BRCA1 germline mutation. Research has shown that denosumab may also reduce the risk of developing breast cancer in women carrying a BRCA1 germline mutation.
The research study is being conducted to test the long-term safety, tolerability and effectiveness of rozanolixizumab in adult patients with generalized myasthenia gravis (MG) who have already taken part in the MG0003 study and is intended to replace MG0004. This study will evaluate 6-week treatment cycles of rozanolixizumab in study …
The research study is being conducted to determine the safety and effectiveness of an investigational device, the Edwards PASCAL Transcatheter Valve Repair System (hereinafter referred to as the PASCAL System), with optimal medical therapy (OMT) compared to optimal medical therapy alone in the treatment of patients with symptomatic, severe tricuspid …
The research study is being conducted to determine the effectiveness of using hyperpolarized xenon-129 magnetic resonance imaging (MRI) in diagnosing and predicting treatment outcomes for patients who received endobronchial valve (EBV) therapy to treat chronic obstructive pulmonary disease (COPD). COPD is a disease of the lungs caused most often by …
The aim of the pilot study is to demonstrate feasibility and tolerability of semaglutide in patients with obesity and advanced ILD.
We are researching whether sildenafil (or a placebo) can improve cerebrovascular reactivity (CVR) in the brain for individuals with ongoing symptoms from a brain injury. CVR is the brain's ability to adjust blood vessel size to maintain proper blood flow based on its oxygen needs. Sildenafil, commonly known as Viagra, …
The purpose of this study is to test a new scanner device that combines two types of imaging called Breast Positron Emission Tomography (BPET) and Digital Breast Tomosynthesis (DPT) for imaging of a radioactive imaging drug called 18F-Fluoroestradiol (FES), as a diagnostic device for imaging estrogen receptor (ER) positive breast …
This research study is being conducted to evaluate experimental rescue therapies for the treatment of cytokine release syndrome (CRS) and CAR T cell related HLH-like syndrome (CRHLS). These are both life-threatening side effects which can occur in some patients after infusion with a CAR T cell product. This consent allows …
