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Found 930 All Conditions trials

A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

 Whole-Brain Spectroscopy Guided Personalized Delivery of Tumor Treating Fields in Glioblastoma Patients
22-99 years
All genders
The research study is for Glioblastoma (GBM) patients beginning Optune, a therapy that uses - tumor treating fields (TTFields). As a part of this study participants will either receive Optune with standard treatment array mapping from MR imaging or an alternative treatment array mapping based on advanced MR imaging also …
 PBFT02-001- Phase 1B Study to Assess a Single Dose of PBFT02 Delivered into Adult Subjects with Fronto-Temporal Dementia (FTD) and Mutations in the Progranulin Gene (GRN)
35-75 years
All genders
Phase 1
This research is being done to study a new way to treat FTD in patients who have the GRN mutation. This process is called “gene therapy”. Gene therapy is an experimental technique that aims to replace the gene that is not working properly with a version of the gene that …
 Myeloid derived suppressor cell expression in newborn infants: an observational cohort study
1-1 years
All genders
This research study is being conducted to study a type of white blood cells called MDSC in newborn babies. These cells help regulate our body’s immune system. Learning more about these cells may help us to better understand immune function in newborn babies.
 PRESTA- Promoting Recovery after Stroke with Amantadine
18-99 years
All genders
Phase 2
The research team aims to examine whether amantadine can help patients recover from stroke. This will be a blinded randomized clinical trial. We will randomize patients post-ischemic or hemorrhagic stroke either to the placebo arm or amantadine. Patients will be on study drug or placebo for 1 month but will …
 Analyses of candidate fluid biomarkers in schizophrenia and bipolar spectrum disorders: Prioritizing mechanisms nominated by genetics
18-50 years
Accepts healthy volunteer
All genders
The purpose of this research study is to identify biological markers for schizophrenia and bipolar spectrum disorders and related mental illnesses. This information may enable us in the future to develop interventions to improve symptoms and functions or worsening of symptoms.
 A study to evaluate the impact of cariprazine (1.5mg) on cocaine use in OUD-CocUD patients on  buprenorphine-naloxone.
18-65 years
All genders
Phase 2
The research study is being conducted to understand whether the medication, cariprazine, affects drug use, and brain and behavioral responses in people with opioid and cocaine use disorder already being treated with the medication buprenorphine-naloxone (brand names: Suboxone, Zubsolv, Bunavail). Cariprazine (VRAYLAR ) is FDA-approved for the treatment of certain …
 Brain Arterio-Venous Metabolomic Profiling
18-99 years
All genders
The research study is being conducted to better understand brain metabolism, i.e. how the brain uses and consumes the various nutrients that are available in the blood. Changes in brain metabolism have been implicated in dementia and psychiatric disorders, as well as short- and long-term outcomes of traumatic brain injury …
 Innovative Combination Immunotherapy for Metastatic Triple Negative Breast Cancer (TNBC)
18-99 years
Female
Phase 2
This phase II trial studies how well avelumab in combination with binimetinib, utomilumab, or anti-OX40 antibody PF-04518600 works in treating patients with triple negative breast cancer that is stage IV or is not able to be removed by surgery (unresectable) and has come back (recurrent). Immunotherapy with checkpoint inhibitors like …
 TEGSEDI Administration in Patients with Polyneuropathy of Hereditary Transthyretin-mediated Amyloidosis (hATTR-PN)
18-99 years
All genders
Phase 4
TEGSEDI (also known as inotersen) is a medicine that has been approved in the United States, Europe and Canada to treat polyneuropathy (nerve damage) caused by hereditary transthyretin amyloidosis (hATTR-PN) in adults. hATTR-PN is a rare genetic disease that worsens over time if left untreated. This research study will examine …
 Study to Evaluate the Efficacy and Safety of CTP-543 in Adult Patients With Moderate to Severe Alopecia Areata
18-65 years
All genders
Phase 3
Interventional
This is a multi-center Phase 3 study to evaluate the safety and effectiveness of an investigational study drug (called CTP-543) in adults (18 years and older) who have 50% or greater scalp hair loss. The study is placebo-controlled, meaning that some patients entering the study will not receive active study …
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