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Found 938 All Conditions trials

A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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TEGSEDI Administration in Patients with Polyneuropathy of Hereditary Transthyretin-mediated Amyloidosis (hATTR-PN)
18 years - 99 years
All genders
Phase 4
TEGSEDI (also known as inotersen) is a medicine that has been approved in the United States, Europe and Canada to treat polyneuropathy (nerve damage) caused by hereditary transthyretin amyloidosis (hATTR-PN) in adults. hATTR-PN is a rare genetic disease that worsens over time if left untreated. This research study will examine …
Study to Evaluate the Efficacy and Safety of Nefecon Treatment in Patients With IgA Nephropathy Who Have Completed Study Nef-301
18 years - 99 years
All genders
Interventional
This is a Phase 3b, multicenter, open-label extension (OLE) study to evaluate the efficacy and safety of Nefecon treatment in patients with IgAN who have completed the Phase 3 Study Nef 301 and continue to be treated with a stable dose of RAS inhibitor therapy (ACEIs and/or ARBs). Patients who …
Size and Decay of HIV-1 Reservoirs in Tissues and Cerebrospinal Fluid in Participants on Long-Term Antiretroviral Therapy
18 years - 99 years
All genders
The purpose of this study is to look at where human immunodeficiency virus (HIV) might be “hiding” when standard lab tests show that HIV levels in the blood are very low.
Studying symptomatic Transthyretin Amyloid Cardiomyopathy for those who Completed the Phase 3 ATTRibute-CM Trial (AG10-301)
18 years - 99 years
All genders
Phase 3
This open-label study is designed to evaluate the long-term safety and tolerability of acoramidis in participants with ATTR-CM, administered on a background of stable heart failure therapy. This study follows the randomized, double-blind, placebo-controlled Study AG10-301 which was designed to examine safety and efficacy in this same population.
UPCC 22921 An Open-Label, Multicenter, First-in-Human, Dose-Escalation Phase 1 Study of INBRX-109 in Subjects With Locally Advanced or Metastatic Solid Tumors Including Sarcomas
12 years - 85 years
All genders
Phase 1
Interventional
This study investigates the effects of an investigational medication targeting advanced or metastatic solid tumors, including sarcomas. The purpose of this research is to understand how the investigational medication, a recombinant humanized tetravalent antibody, interacts with the human death receptor 5 (DR5). The study aims to explore its potential therapeutic …
Validation of the prospective registry of outcomes in patients electing lung transplantation (PROPEL)
18 years - 99 years
All genders
The research study is being conducted to develop a test to predict a common complication after lung transplant called primary graft dysfunction (PGD). Predicting PGD before using donor organs may help reduce deaths and improve outcomes of patients receiving a lung transplant in the future.
Potential Role of FDG-PET-CT in Assessing Cardio-Vascular-Pulmonary  CNS and Other Complications of COVID-19 Infection
18 years - 99 years
All genders
The research study is being conducted to assess the role of Fluorodeoxyglucose (FDG)-Positron Emission Tomography (PET) imaging (a radiology scan) for monitoring the course of COVID-19 infection.
UPCC 04221 Collection of Samples from the United States Population for Optimization and Evaluation of Colorectal Cancer (CRC) Plasma Circulating Free-DNA (cfDNA) Marker Panel Performance (USOPTIVAL)
45 years - 84 years
Accepts healthy volunteer
All genders
This study investigates the use of circulating free-DNA (cfDNA) markers in blood to improve detection of colorectal cancer (CRC) and advanced adenomas. The purpose of this study is to collect blood samples and clinical data from participants in order to optimize a biomarker panel for better detection of these conditions.Participants …
UPCC 08821 Evaluating in vivo PARP-1 expression with 18F-FluorThanatrace positron emission tomography (PET/CT) in Patients with Metastatic Prostate Cancer
18 years or above
Male
Observational
This study investigates PARP-1 expression in men with metastatic prostate cancer using a special imaging technique called PET/CT scans. The purpose of this study is to observe how a radiotracer, which is a substance used to highlight areas of the body in imaging tests, interacts with cancerous sites in the …
A  study of near infrared imaging of myocardial scar and epicardial ganglionated plexus in patients undergoing cardiac surgery
18 years - 99 years
All genders
Observational
To determine the feasibility of near infrared (NIR) imaging of myocardial scar and epicardial adipose tissue in patients undergoing cardiac surgery.
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