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Found 938 All Conditions trials

A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Understanding the Genetics of Central Centrifugal Cicatricial Alopecia
99 years or below
All genders
The purpose of this study is to characterize gene mutations associated Central Centrifugal Cicatricial Alopecia (CCCA). The Penn Medicine BioBank (PMBB) supports researchers by providing centralized access to a large number of annotated blood and tissue samples. Clinician identified patients with CCCA and appropriate controls will be recruited from the …
99 years or below
All genders
Phase 1
This is an investigator-initiated, open label phase Ib study examining 2nd line atezolizumab and tocilizumab in a cohort of recurrent/metastatic non-small cell lung cancer patients who have received prior immune checkpoint inhibitor therapy with or without other forms of therapy (i.e. chemotherapy, radiation). Patients with driver mutations in EGFR, ALK, …
99 years or below
All genders
To support the research of lymphoproliferative disorders (LPDs) by supplementing the main repository (IRB #832203) with biospecimens (i.e., tissue and fluid) obtained solely for the purpose of research. These materials will be used for future, unspecified research.
A Clinical Trial to Evaluate the Safety and Efficacy of Staged Bilateral Exablate Treatment of Medication Refractory Essential Tremor
99 years or below
All genders
The Exablate Model 4000 Type-1.0/1.1 Neuro system involves using an advanced, non-invasive technique currently approved by the Food and Drug Administration (FDA) to treat one side of your brain in a procedure called a thalamotomy (lesion the thalamus). This procedure involves performing an ablation (lesion) of an area of the …
UPCC 28920 A Study to Evaluate the Safety and Efficacy of Image Guided Surgery using Indocyanine Green for Intramolecular Imaging of Solid Tumors Compared to Standard of Care, (TumorGlow™)
18 years or above
All genders
Phase 1/2
Interventional
This study investigates the use of image-guided surgery with indocyanine green for imaging solid tumors. The purpose is to evaluate the safety and effectiveness of this method compared to the standard surgical care. Patients involved are those with solid tumors or diseased tissue, including benign nodules, which are considered resectable …
CHARM- Phase 3 Study to Evaluate the Efficacy and Safety of Intravenous BIIB093 (Glibenclamide) for Severe Cerebral Edema following Large Hemispheric Infarction
18 years - 99 years
All genders
Phase 3
Interventional
This is a Phase 3 study, which means that BIIB093 (study drug) has already been investigated in previous clinical research studies with a small number of people with large hemispheric infarction (LHI). These studies suggested that the study drug was safe, did not cause serious side effects or discomfort, and …
TAMBE- Evaluation of the GORE EXCLUDER Thoracoabdominal Branch Endoprosthesis in the Treatment of Thoracoabdominal and Pararenal Aortic Aneurysms
18 years - 99 years
All genders
Normal 0 false false false EN-US JA X-NONE Patients with thoracoabdominal or pararenal aneurysm disease will be asked to take part in this research study This research study will look at treating thoracoabdominal or pararenal aneurysm disease with a new stent-graft design. The reason we are doing this research study …
35 years - 50 years
Female
Interventional
This study investigates the effectiveness of two surgical procedures in reducing the risk of ovarian cancer in individuals with BRCA1 mutations. The purpose of this study is to compare bilateral salpingectomy, which involves removing the fallopian tubes, with bilateral salpingo-oophorectomy, which involves removing both the fallopian tubes and ovaries. These …
A Randomized study of EHR Defaults and Using social Comparison feedback to Effectively decrease opioid prescription pill burden - The REDUCE Trial
99 years or below
All genders
Observational
Opioid-related abuse and overdose represent a growing national epidemic in the United States. Clinician practice patterns play an important role: opioid prescriptions impact the likelihood that patients will misuse or become dependent on these medications, with longer prescriptions leading to greater sustained use. In this study, we will evaluate a …
18 years or above
All genders
Phase 2
Interventional
This study investigates the effects of investigational medications like hydroxychloroquine and avelumab, with or without palbociclib, on early-stage ER+ breast cancer patients. These patients have disseminated tumor cells (DTCs) in their bone marrow after surgery and standard therapy. The purpose is to understand how these medications can target DTCs, which …
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