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Found 938 All Conditions trials

A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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A Multicenter Randomized Controlled Trial of Best Available Therapy versus Autologous Hematopoietic Stem Cell Transplant for Treatment-Resistant Relapsing Multiple Sclerosis (BEAT-MS)
18 years - 55 years
All genders
The purpose of this study is to compare efficacy and safety of Autologous Hematopoietic Stem Cell Transplant (AHSCT) to best available therapy (BAT) in relapsing MS. Best available therapy is referring to the best available medications that are used to treat MS. Patients who agree to participate in the experimental …
Prospective 4D Computed Tomography Angiography Of The Bicuspid Aortic Valve Apparatus: A Comparison Of Bicuspid Aortic Valves With And Without Aortic Insufficiency
99 years or below
All genders
The purpose of this study is to characterize the differences in the aortic valve and aortic root anatomy in patients with BAVs in order to better understand the anatomical features that allow the BAV to function normally. With this information, surgeons and cardiologists will be better able to determine which …
40 years - 80 years
All genders
The research study is being conducted to determine the utility of magnetic resonance imaging (MRI) in identifying inflammation of arteries supplying blood to the head, brain, and eyes, which may be useful in the diagnosis, prognosis, and treatment of giant cell arteritis (GCA; temporal arteritis). Study participants are eligible if …
99 years or below
All genders
Phase 2
The research study is being conducted to help physicians understand if apremilast, an oral medication, is effective in treating recurrent oral erythema multiforme (EM). Study consists of four research study visits (weeks 0,6. 12, 24, 36) and completion of a daily treatment diary during the 24 week tratment period. Week …
99 years or below
All genders
Prospective, randomized, blinded clinical trial is to assess the safety and efficacy of the CARILLON Mitral Contour System in treating functional mitral regurgitation associated with heart failure.
Matching Perfusion and Metabolic Activity in HFpEF
18 years - 99 years
All genders
Phase 2
The goal of the MPMA Study is to test whether Potassium Nitrate, with and without Propionyl-L-Carnitine and Nicotinamide Riboside, improves submaximal exercise endurance and skeletal muscle oxidative phosphorylation capacity in participants with Heart Failure with Preserved Ejection Fraction. We are assessing whether these supplements, either together or separate, help relieve …
Effect of GLP-1 Agonist Therapy on Insulin Secretion in Adults with Pancreatic Insufficient Cystic Fibrosis and Abnormal Glucose Tolerance: a randomized  open-label  cross-over trial
18 years - 50 years
All genders
The research study is being conducted to better understand Cystic-Fibrosis Related Diabetes (CFRD) and to see the effects of an analog of the gut incretin hormone, GLP-1 (dulaglutide), has on individuals like with abnormal glucose tolerance. GLP-1 (dulaglutide) helps the pancreas release insulin, which controls blood sugar levels from getting …
RECOVER: Safety and Effectiveness of VNS Therapy  System as Adjunctive Therapy Versus a No Stimulation Control in Subjects With Treatment-Resistant Depression
18 years - 99 years
All genders
The research study is being conducted to determine if active VNS (Vagus Nerve Stimulation) Therapy helps depression subjects compared to a no-stimulation control group. This trial has is currently only recruiting bipolar subjects. Patients with an established diagnosis with Treatment-Resistant Depression (TRD), Bipolar I or II, and have been referred …
Noninvasive Quantification of Renal Oxygen Utilization in Early Kidney Disease
18 years - 59 years
Accepts healthy volunteer
All genders
Type 2 diabetes is the most common cause of chronic kidney disease (CKD). In people with diabetes, the kidneys do not function normally and continuously require more oxygen to remove waste from the body. This process, in-turn, depletes the available supply of oxygen, causes damage to the tissue itself, and …
PBFT02-001- Phase 1B Study to Assess a Single Dose of PBFT02 Delivered into Adult Subjects with Fronto-Temporal Dementia (FTD) and Mutations in the Progranulin Gene (GRN)
35 years - 75 years
All genders
Phase 1
This research is being done to study a new way to treat FTD in patients who have the GRN mutation. This process is called “gene therapy”. Gene therapy is an experimental technique that aims to replace the gene that is not working properly with a version of the gene that …
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