Found 930 All Conditions trials
A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
Elevations in plasma levels of branched chain amino acids (BCAAs, comprising leucine, valine, and isoleucine), a large component of protein, are strongly associated with insulin resistance and type 2 diabetes, but mechanisms for this relationship are unclear. This protocol will determine whether excess BCAAs worsen free fatty acid-induced insulin resistance. …
This study aims to investigate the benefits of collecting lymph in addition to blood in patients with multiple sclerosis (MS). It is now well recognized that the central nervous system (CNS) is not as immune privileged as it has been considered. A system of lymphatic drainage has been described both …
The purpose of this study is to evaluate the therapeutic benefit for participants receiving Recovery-Oriented Cognitive Therapy (CT-R) for families- a cognitive therapy based group for family members of individuals in the early stages of psychosis. A CT-R based intervention has shown to be effective for individuals with psychosis, offers …
The study is at the Penn Memory Center at the University of Pennsylvania and is under the direction of David Wolk, M.D.. We are currently recruiting normal control participants ages 75 years and older. The purpose of this study is to collect, store and analyze cognitive data and biological samples, …
To achieve all of our research objectives, we plan to conduct a pilot study of a CDS intervention, exposing half of our clinician sample to the TUT Service+VM condition during cancer care workflow, and comparing important outcome measures to those observed among the half exposed to the current usual care …
Do you have high nighttime blood pressure? Are you healthy, but interested in having a blood pressure study? Penn Medicine is seeking study participants 18years of age and older to have their blood pressure, physical activity, mobility, heart health, and social behavior monitored over 24 hours on two occasions. This …
To determine if catheter-based atrial fibrillation (AF) ablation is superior to treatment with antiarrhythmic drugs as a first-line therapy for symptomatic persistent AF
Dr. Amit Bar-Or, MD, FRCPC from the University of Pennsylvania Department of Neurology is conducting a study to investigate how the structure and activity of gastrointestinal microbes (bacteria and fungi) found in the gut contribute to multiple sclerosis pathogenesis. You are being asked to participate in this study because either …
This is a Phase I study evaluating the safety and feasibility of intraperitoneal administered lentiviral transduced MOv19-BBz CAR-T cells in 4 cohorts with or without cyclophosphamide + fludarabine in a 3+3 dose escalation design. Up to 18 evaluable subjects will be treated.
We are conducting research studies on how immune system cells contribute to inflammatory conditions of the nervous system, such as multiple sclerosis, neuromyelitis optica (NMO), encephalitis, head injury, epilepsy, Parkinson's disease (PD), Alzheimer's disease (AzD), Lou Gherig's disease (amyotrophic lateral sclerosis; ALS) frontotemporal dementia (FTD) and others. This includes investigating …
