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Found 938 All Conditions trials

A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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99 years or below
All genders
Hydrocephalus is a medical condition in which an abnormal buildup of cerebrospinal fluid (CSF) causes the fluid-filled spaces of the brain, the ventricles, to become enlarged. Enlarged ventricles and increased intracranial pressure can cause headaches, dizziness, blurred vision, cognitive impairment, gait disturbances and in severe cases even brain herniation or …
18 years or above
All genders
Phase 1/2
Interventional
This study investigates the use of a radiation boost in combination with immune checkpoint blockade therapy in patients with operable breast cancer. The purpose is to determine if combining pembrolizumab, an immune therapy, with a single radiation boost is feasible and effective. The study will track changes in tumor size …
18 years or above
All genders
Phase 1
Interventional
This study investigates the use of PET/CT imaging to evaluate the uptake of a special substance called [18F]F-Gln in patients with breast cancer. This study includes patients with known or suspected primary or metastatic breast cancer, which means the cancer may have spread to other parts of the body. The …
Testing of Magnetic Resonance Methods at 7.0 Tesla
18 years - 60 years
All genders
Observational
The research study will test the performance of new magnetic resonance imaging and spectroscopy techniques at 7.0 Tesla. These new methods have already been tested in model systems and need to be tried on human subjects prior to use in patient population.
Identification of neoantigen-specific T cell responses in cancer patients within the Penn Medicine BioBank
18 years - 90 years
All genders
You are being asked to participate in this research investigation because you have expressed an interest in participating in a study to better understand how the immune cells of the body recognize and fight cancer.
18 years - 80 years
All genders
The purpose of this study is to learn how to dialysis doctors can treat dialysis patients infected with Hepatitis C themselves. Hepatitis C infection is common in hemodialysis patients. There are new medications, such as Zepatier, which can cure hepatitis C in > 95% of patients. Zepatier is particularly good …
UPCC 04219 Phase 2 Study of Capecitabine-Temozolomide(CapTem) with yttrium-90 Radioembolization in the Treatment of Patients with Unresectable Metastatic Grade 2/3 Neuroendocrine Tumors
18 years or above
All genders
Phase 2
Interventional
This study investigates the treatment of patients with unresectable metastatic neuroendocrine tumors (NETs) that are primarily located in the liver. The purpose of this study is to evaluate the effectiveness and safety of a combination treatment using Capecitabine-Temozolomide (CapTem) and yttrium-90 (Y90) radioembolization.Participants in the study will receive CapTem, which …
Cardiometabolic Effects of Dipeptidyl Peptidase IV and Related Pathways
18 years - 99 years
All genders
DPP4 is an enzyme that breaks down proteins that may affect blood sugar and the heart. We will recruit individuals from the Penn Biobank (cases, controls). Participants will be asked to complete a meal test, DXA, and echocardiogram with exercise. A cardiac MRI and related pilot study are optional.
Surgical Therapy for Obstructive Sleep Apnea on Blood Pressure & Peripheral Arterial Tonometry
18 years - 90 years
All genders
The research study is being done to look at the effect of sleep apnea surgery on different measures ofcardiovascular (heart) function in people with obstructive sleep apnea.
99 years or below
All genders
Lynch syndrome (LS) is a cancer predisposition syndrome that results from a pathogenic germline mutation in one of five genes, including MLH1, MSH2, MSH6, PMS2, and EPCAM, which are involved in DNA mismatch repair (MMR). Individuals with Lynch syndrome develop cancer at a substantially higher rate than individuals without LS …
361 - 370 of 938