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Found 930 All Conditions trials

A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

ATHENA

99 years and younger
All genders
A research study looking into how ziltivekimab works compared to placebo in people with heart failure and inflammation
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NN111: ExTINGUISH

99 years and younger
All genders
This is an interventional, randomized control, clinical trial involving inebilizumab (investigational drug, given only at two timepoints by infusion) in patients with anti-NMDA receptor encephalitis. The purpose is to determine the difference in modified Rankin score at 16 weeks in participants with anti-NMDA receptor encephalitis treated with 'first-line' immunomodulatory therapies …
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UPCC 14023 CARTIMMUNE: A Single-Center Study of Patients with Autoimmune Diseases Receiving an Autologous Fully-Human Anti-CD19 Chimeric Antigen Receptor T-Cell (KYV 101)

99 years and younger
All genders
The purpose of this study is to assess the safety, tolerability, and clinical activity of KYV-101 (a fully-human anti-CD19 CAR T-cell therapy) in adult subjects with B cell-driven autoimmune diseases. The diseases under study include: idiopathic necrotizing myopathy (INM) consisting of dermatomyositis (DM), necrotizing myopathy, anti-HMGCoA-associated myopathy, and polymyositis (PM), …
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Individualized monitoring post-amyloid clearing therapy

99 years and younger
All genders
Primary Objective: To determine changes in neurodegeneration over the first year of treatment with anti-amyloid monoclonal antibodies Secondary Objectives: To identify measures that detect and monitor neuroinflammation during anti-amyloid treatment. To explore the interaction between neuroinflammation and neurodegeneration Primary Endpoint: Neuroimaging and blood-based measures of neurodegeneration, cognitive performance Secondary Endpoints: …
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Adaptation and Feasibility of the Community-Based Anxiety Program Tailored for Autism (CAPTA)

7-17 years
All genders
Anxiety is very common in autistic youth. Recently, an intervention has been created by the investigators to target these symptoms in autistic youth in a community setting. The purpose of this study is to determine the feasibility of implementing this treatment in community care centers.
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Intraoperative Electrophysiological Recordings and Non-Invasive Wearable Sensors for Movement Capture During Awake Brain Surgery

18-75 years
All genders
Objective:To conduct electrophysiological experiments in human patients undergoing awake brain surgery with the aim of elucidating how the various brain regions coordinate their activity during naturalistic movements.Evaluate the effectiveness of various electrode arrays for recording of cortical activity.How the brain coordinates body movements and processes sensations such as touch.How the …
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Epithelial Barrier

99 years and younger
All genders
The purpose of this study is to investigate the presence of tight junctions in gingiva of individuals with periodontitis and peri-implantitis compared to non-inflamed gingiva. We will examine the presence of tight junctions identified by E-cadherin and Zo1 in both periodontitis and peri-implantitis compared to that without inflammation. We will …
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LGH IRB 2022-27: Phase 2 Study of ZNc3 in High-Grade Serous Ovarian Cancer

99 years and younger
All genders
This study will evaluate safety, clinical activity, and PK of ZN-c3 in subjects with platinum-resistant, high grade, serous ovarian, fallopian tube, or primary peritoneal cancer. Part 1a locally advanced/metastatic solid tumors with mutations in MRN complex genes or CCNE1 gene amplification. Part 1b primary peritoneal cancer. Part 2: PROC allocated …
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IMPROVE-AD

99 years and younger
All genders
The primary objective of the IMPROVE-AD trial is to determine whether an upfront invasive strategy of TEVAR plus medical therapy reduces the occurrence of a composite endpoint of all-cause death or major aortic complications compared to an upfront conservative strategy of medical therapy with surveillance for deterioration in patients with …
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MyPEAK-1

99 years and younger
All genders
Please see section 2 of the full protocol Please see section 2 of the full protocol Please see section 2 of the full protocol
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