Found 930 All Conditions trials
A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
Systemic sclerosis is a rare chronic autoimmune connective tissue disease. B cells have been reported to play a central role in the pathogenesis of SSc and B cell depletion has been shown to offer benefit to patients with SSc. Belimumab is a monoclonal antibody, which inhibits the survival of B …
The study compares FAM-HELP to standard HELP for preventing delirium and related complications. Patients 70 and older along with their family/caregiver will be enrolled. HELP is standard care at HUP using interventions such as multicomponent nonpharmacologic strategies targeting delirium risk factors. FAM-HELP provides similar interventions, with family/caregiver augmenting HELP based …
The purpose of this study is to investigate the responses of the brain region known as the subgenual anterior cingulate cortex (sgACC) during transcranial magnetic stimulation (TMS) in individuals with depression. Specifically, investigators aim to determine whether the sgACC is engaged when TMS is delivered to specific targets and if …
Please see section 3 of the full protocol Please see section 3 of the full protocol Please see section 3 of the full protocol
The main purpose of this study is to learn how well the investigational drug NS-229 works and how safe NS-229 is compared with placebo. An investigational drug is one that is not approved by the United States Food and Drug Administration (FDA) to treat EGPA. Participants could be in the …
The overall study objectives include evaluating the long-term safety and tolerability of Staccato alprazolam in patients with stereotypical prolonged epilepsy. The study will evaluate the probability of success of repeated treatment with Staccato alprazolam and of repeated treatment with Staccato alprazolam with no recurrence of seizure(s) up to 2 hours …
The primary aim of this trial is to test in a randomized double-blind placebo-controlled study whether abatacept, administered concurrently with corticosteroids, is associated with a reduction in major cardiovascular events among participants with recently diagnosed ICI myocarditis.
The study is designed to evaluate the efficacy and safety of intraputaminal delivery of AAV2-GDNF gene therapy in subjects with moderate Parkinson's disease and demonstrate proof-of-concept. Subjects will be randomized to 1 of 2 treatment arms, AAV2-GDNF surgery or control surgery and will undergo screening, two baseline visits, perioperative procedures, …
The purpose of this study is to evaluate the safety and efficacy of TCD601 (siplizumab), an anti-CD2 monoclonal antibody, in combination with a CNI-free regimen of belatacept, mycophenolic acid (MPA) and corticosteroids compared to a standard of care CNI-based regimen of tacrolimus, ATG, MPA and corticosteroids in de novo renal …
I am requesting a reliance agreement with the external IRB Advarra. The purpse is to treat a single patient with gastroparesis who has requested expanded access with tradipitant.By doing so, we will also monitor the efficacy of tradipitant in reducing individual symptoms associated with gastroparesis in this single patient and …
