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Found 36 stroke trials

A listing of stroke medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

 CHARM- Phase 3 Study to Evaluate the Efficacy and Safety of Intravenous BIIB093 (Glibenclamide) for Severe Cerebral Edema following Large Hemispheric Infarction

CHARM- Phase 3 Study to Evaluate the Efficacy and Safety of Intravenous BIIB093 (Glibenclamide) for Severe Cerebral Edema following Large Hemispheric Infarction

18-99 years
All genders
Phase 3
Interventional
This is a Phase 3 study, which means that BIIB093 (study drug) has already been investigated in previous clinical research studies with a small number of people with large hemispheric infarction (LHI). These studies suggested that the study drug was safe, did not cause serious side effects or discomfort, and …
 Spironolactone for Regulating Blood Pressure after Intracerebral Hemorrhage

Spironolactone for Regulating Blood Pressure after Intracerebral Hemorrhage

18-99 years
All genders
Blood pressure treatment is important for all survivors of intracerebral hemorrhage (ICH). High blood pressure after ICH puts patients at high risk for future strokes and memory problems. Nearly all doctors agree that patients  who have had a brain hemorrhage should be treated with blood pressure medications. But doctors are …

Intellia NTLA-2001

99 years and younger
All genders
To evaluate the efficacy of NTLA-2001, as measured by the composite risk of CV-related mortality and CV events (urgent HF visits and hospitalizations due to HF, MI, arrhythmia, or stroke), compared to placebo Composite endpoint comprising Cardiovascular related mortality and frequency and timing of Cardiovascular events (urgent Heart Failure visits …

CT evaluation of carotid plaque components

99 years and younger
All genders
Specific Aim 1: To validate the diagnostic performance of photon counting/spectral CT to distinguish plaque tissue components in patients with ischemic stroke/transient ischemic attack (TIA) and are treated medically against (1) carotid MRI and (2) plaque segmentation software of the PCCTA images. Specific Aim 2: To validate the diagnostic performance …

CAPTIVA

99 years and younger
All genders
CAPTIVA is a two-stage Phase III trial randomizing subjects with stroke attributed to 70-99% intracranial atherosclerotic stenosis (sICAS) to: 1) ticagrelor + aspirin 2) low dose rivaroxaban + aspirin 3) clopidogrel + aspirin Subjects will be followed for a year.

ROMA: Women

99 years and younger
All genders
The primary aim is to conduct a multicenter international randomized control trial to test the hypothesis that the use of a two or more AGs compared to a single arterial graft is associated with a reduction in the composite outcome of death from any cause, any stroke, post discharge myocardial …

CARSK

99 years and younger
All genders
CARSK aims to test the hypothesis that after screening for wait list entry, no further screening for coronary artery disease (CAD) is non-inferior to the current standard care, which is screening all asymptomatic wait-listed patients for CAD at regular intervals, and to compare the benefits and costs of not screening …
 Non-Dipping Hypertension and The Human Chronobiome

Non-Dipping Hypertension and The Human Chronobiome

18-99 years
All genders
Phase 1
Interventional
Do you have high nighttime blood pressure? Are you healthy, but interested in having a blood pressure study? Penn Medicine is seeking study participants 18years of age and older to have their blood pressure, physical activity, mobility, heart health, and social behavior monitored over 24 hours on two occasions. This …

RURAL Heart and Lung Study

99 years and younger
All genders
People living in impoverished counties in the rural South have the lowest life expectancy in the United States, and the highest mortality rates due to heart, lung, blood and sleep disorders, stroke, and cancer. RURALs innovative design seeks to overcome these challenges with its unique study design that brings resources …
 Brain Arterio-Venous Metabolomic Profiling

Brain Arterio-Venous Metabolomic Profiling

18-99 years
All genders
The research study is being conducted to better understand brain metabolism, i.e. how the brain uses and consumes the various nutrients that are available in the blood. Changes in brain metabolism have been implicated in dementia and psychiatric disorders, as well as short- and long-term outcomes of traumatic brain injury …
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