Found 938 All Conditions trials
A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
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This first-in-human phase 1 clinical trial will evaluate two immunogens designed to induce HIV-1 envelope (Env) V2 apex-specific broadly neutralizing antibodies (V2 apex bnAbs). Both vaccines consist of a modified mRNA encapsulated in lipid nanoparticles (LNP) that when translated in cells produces HIV-1 Env gp150 transmembrane trimers
The purpose of this study is to assess the efficacy and safety of RO7790121 (formerly PF-06480605 and RVT-3101) in patients with moderately to severely active Crohn's disease (CD). RO7790121 is a fully human neutralizing immunoglobulin G1 (IgG1) monoclonal antibody (mAb) against tumor necrosis factor-like ligand 1A (TL1A)
The study will be a prospective, multi-center, non-randomized trial with all subjects enrolling into a single arm receiving the inQB8 MonarQ TTVR system. Subjects suffering from severe or greater, symptomatic tricuspid regurgitation who are anatomically suitable for the MonarQ device and who have been determined to be intermediate or high …
This is a global, multicenter, prospective, observational study designed to document clinical characteristics and treatment patterns of adult patients with ATTR-CM treated with vutrisiran or other approved ATTR-CM treatments and to evaluate long-term effectiveness of vutrisiran compared to other approved ATTR-CM treatments. Data will be collected retrospectively and prospectively from …
-To establish a biospecimen repository including lymph node aspirates, lymph node cores, bone marrow aspirates, adenoid swabs, and paired blood samples from individuals with immune disorders, vaccinated individuals, and healthy controls. -To create a linked clinical database capturing relevant participant information, enabling correlation of biological characteristics with clinical features. This …
Researchers at Monell Chemical Senses Center are conducting research on how eating behavior is influenced by internal body states and external food-related states. We are looking for healthy young adults (18 to 45) to participate in this study.
We are requesting a reliance agreement for an external IRB to serve as the single IRB. This study will determine the impact of body composition on perioperative and patient-centered outcomes among adults being evaluated for lung transplantation. Pre-transplant, subjects will complete a survey to assess their health-related quality of life …
This is a multi center study run out of the University of Pittsburgh by Dr Traci Kazmerski; it attempts to assess the effect of parenthood on persons with cystic fibrosis, both men and women; the study obtains already existing registry data and utilizes questionnaires and interviews for the parents to …
A greater understanding of (1) dietary intake, (2) micronutrient status, and (3) bone density with GLP obesity treatment will highlight potential gaps in care and opportunities for nutrition support. The purpose of this cross-sectional study is to assess the nutrition status of patients prescribed a maintenance dose of semaglutide treatment …
Increasing evidence points to the existence of a gut-eye axis, with alterations in the intestinal microbiome composition and its byproducts linked to a multitude of prevalent ocular diseases The purpose of this study is to describe the intestinal microbiome composition patients with a variety of ocular diseases by establishing a …
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