Found 938 All Conditions trials
A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
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This is a study to evaluate AB-1009 (IP under study) in adult patients with late-onset pompe disease (LOPD). LOPD is caused by a genetic mutation resulting in a decrease in the GAA enzyme, resulting in the destruction of muscle tissue. AB-1009, administered as a one-time IV dose, is an gene …
The objectives of the Randomized Arm are 1) Demonstrate improvement in survival when non-inotrope dependent advanced HF patients are treated with the HM3 left ventricular assist system (LVAS) compared to being managed on medical therapy alone; and 2) To establish an objective disease-state criteria to trigger referral for a HM3 …
Requesting a reliance agreement with an external IRB. The purpose of this open-label extension trial is to evaluate the long-term safety and efficacy of treatment with plozasiran on the reduction of fasting serum TG from Baseline in subjects with Severe Hypertriglyceridemia.
This study examines the safety, tolerability, and effectiveness of AZD2373 in APOL1-Mediated Kidney Disease (AMKD). Some people have a variant in the APOL1 gene that is associated with protection against African sleeping sickness but increases the risk of kidney disease in some people. There is currently no approved treatment for …
This study investigates a lab-made antibody called ePGT121v1-LS. The purpose of this study is to see how this antibody works when given alone or with two other antibodies.The study evaluates the safety and effects of these antibodies. It looks at how the body handles the antibody and how well it …
This trial is testing the combination of islatravir (ISL) and ulonivirine (ULO) compared to a treatment called bictegravir/emtricitabine/tenofovir (BIC/FTC/TAF) in people with Human Immunodeficiency Virus (HIV-1). This trial is being done to: Test the safety of the combination of ISL and ULO compared to BIC/FTC/TAF; See how well the combination …
The primary objective is to establish the merit and feasibility of QUTE-CE MRI vascular imaging biomarkers for detecting vascular abnormalities in (n=10) patients with TBI at least 6 months after injury compared to (n=10-16) healthy control (HC) subjects using IV Ferumoxytol as a contrast agent. The single timepoint visit includes: …
This is a Phase III, multi-centre, randomised, double-blind, parallel-group, event-driven study in patients with chronic HF and impaired kidney function who had a recent HF event. The aim is to evaluate the effect of balcinrenone/dapagliflozin vs dapagliflozin, given once daily on top of other classes of SoC, on CV death …
This study investigates the recovery process in women who have undergone Pelvic Organ Prolapse (POP) surgery. Participants will be evaluated using a self-reported recovery questionnaire and will wear an accelerometer on their wrist to monitor activity levels.The study evaluates whether a prescribed exercise regimen after surgery can lead to quicker …
The purpose of this study is to understand how tasting foods affects the body’s early insulin response and blood sugar regulation.
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