Found 938 All Conditions trials
A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
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The primary objectives are to determine the pharmacokinetic (PK) and pharmacodynamic (PD) response of dorzagliatin 75 mg twice daily following 7-day administration in individuals with PI-CF and abnormal glucose tolerance (EGI, IGT or CFRD) when compared to 7-day administration of placebo according to a randomized, double-blind cross-over study design. The …
A5374 is a phase I/IIa randomized, two-arm, double-blind placebocontrolled, multi-step strategy trial to evaluate safety and efficacy of therapeutic vaccination with chimpanzee adenovirus (ChAdV)- and poxvirus modified vaccinia Ankara (MVA)-vectored vaccines in a sequential regimen with the Toll-like Receptor 7 (TLR7) agonist vesatolimod (VES) and two broadly neutralizing antibodies (bNAbs) …
This study investigates ATTR amyloidosis with cardiomyopathy. The purpose of this study is to evaluate the effects of an investigational medication compared to a placebo.This study evaluates the safety and effectiveness of the investigational medication on cardiovascular events and patient-reported health status.Who can participate: Adults with a diagnosis of ATTR …
Living with HIV and struggling with depression or both depression and memory problems?We are looking for participants for a research study comparing two medications: pramipexole extended release (ER) and escitalopram.
This study investigates bronchiectasis. The purpose of this study is to evaluate whether an investigational medication can help people with bronchiectasis.The study evaluates the safety and effectiveness of the investigational medication for people with bronchiectasis. It focuses on understanding how the medication impacts flare-ups and overall health.Who can participate: This …
The purpose of this study is to obtain long-term safety data and long-term maintenance of remission with avacopan treatment in subjects with ANCA associated vasculitis (AAV) on standard of care (SOC) background immunosuppressive therapy. Additionally, health-related quality of life measures and renal function will be assessed. Subjects with severe, active, …
To test if TMS to MRI-guided cortical targets can create neuronal activity changes in downstream regions of interest To determine if TMS-sEEG is a valid research approach to study circuit engagement and specific connections of deep brain nuclei in the human brain To investigate the effects of clinically relevant TMS …
This study investigates the impact of an investigational medication on psoriatic arthritis.The study evaluates the overall impact of the investigational medication on the symptoms and outcomes of psoriatic arthritis. It focuses on understanding how the medication affects the condition in general.Who can participate: Adults 18 years and older with a …
This study investigates pulmonary hypertension associated with interstitial lung disease (PH-ILD) and interstitial lung disease (ILD).The study focuses on understanding patient characteristics, treatment patterns, and clinical outcomes for PH-ILD. It evaluates the disease progression in ILD patients who are at risk for pulmonary hypertension.Who can participate: Adults aged 18 years …
The purpose of this study is to investigate ADPKD, focusing on the PKD1/2 gene variants. The study looks at how common these gene variants are and the characteristics of people who have them.This study evaluates the different traits and demographics of individuals with these gene variants. It explores the clinical …
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