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Found 930 All Conditions trials

A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

A Phase 4 Randomized Open Label Multicenter Prospective Comparative Study To Evaluate The

99 years and younger
All genders
This is a prospective pilot study in which all eligible subjects will be randomized to treatment in the first phase and those with persistent or recurrent heart failure after Phase 1 therapy, may subsequently qualify to be randomized into Phase 2.
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A Single-blind Phase 2 Multi-center Randomized Study to Assess Safety Tolerability Efficacy and Pharmacokinetics of the Relaxin Agonist R2R01 Plus Terlipressin Versus Terlipressin Alone in Patients with Hepatorenal Syndrome-Acute Kidney Injury

99 years and younger
All genders
A Single-blind, Phase 2, Multi-center, Randomized Study to Assess Safety, Tolerability, Efficacy and Pharmacokinetics of the Relaxin Agonist R2R01 Plus Terlipressin Versus Terlipressin Alone in Patients with Hepatorenal Syndrome-Acute Kidney Injury
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A Double-Blinded Randomized Crossover Trial of Stereoencephalography-Guided Multi-Lead Deep Brain Stimulation for Treatment-Refractory Obsessive Compulsive Disorder (SEEG-Guided DBS for OCD)

22-75 years
All genders
Phase 1
This dual-site, double-blinded, randomized, sham-controlled, crossover study is to assess the safety, feasibility, and preliminary efficacy of SEEG-guided multi-lead DBS in 10 participants suffering from severe symptoms of chronic, treatment-refractory OCD. Stage 1: Invasive SEEG Monitoring and Recovery Goal: To perform stimulation mapping studies and SEEG recordings, that aid in …
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NRG-GY026: A Phase II/III Study of Paclitaxel/Carboplatin Alone or Combined With Either Trastuzumab and Hyaluronidase-oysk (HERCEPTIN HYLECTA) or Pertuzumab Trastuzumab and Hyaluronidase-zzxf (PHESGO) in HER2 Positive Stage I-IV Endometrial Serous Carcinoma or Carcinosarcoma

99 years and younger
All genders
This Study tests whether adding trastuzumab and hyaluronidase-oysk (Herceptin HylectaTM) or pertuzumab, trastuzumab and hyaluronidase-zzxf (PhesgoTM) to the usual chemotherapy (paclitaxel and carboplatin) works to shrink tumors in patients with HER2 positive endometrial serous carcinoma or carcinosarcoma. We would like to rely on CIRB as the IRB of record for …
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UPCC 03423: A Phase 1b/2a Open-label Study to Evaluate the Safety Tolerability Pharmacokinetics and Pharmacodynamics of DISC-0974 in Participants with Myelofibrosis and Anemia

99 years and younger
All genders
This phase 1b/2a open-label study will assess the safety, tolerability, pharmacokinetics and pharmacodynamics of DISC-0974 as well as categorize the effects on anemia response in subjects with myelofibrosis and anemia. We would like to rely on Advarra as the IRB of record for this study.
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HIS-BUNDLE CORRECTIVE PACING IN HEART FAILURE

99 years and younger
All genders
The aim is to prospectively evaluate the efficacy and mechanism of benefit of HI-CRT vs. BIV CRT in patients with Right Bundle Brank Block (RBBB). Left Ventricular Ejection Fraction (LVEF) will be assess at 6 months following HIS CRT Vs. BIV CRT implant in Heart Failure patients with RBBB.
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A Phase 2a/b Randomized Double-blind Placebo-controlled Parallel Group Multicenter Clinical Study to Evaluate the Efficacy and Safety of OG-6219 in 3 Dose Levels in Women 18 to 49 Years of Age with Moderate to Severe Endometriosis-related Pain

99 years and younger
All genders
A study to investigate efficacy and safety of OG-6219 BID in 3 dose levels compared with Placebo in participants aged 18 to 49 with moderate to severe endometriosis-related pain
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A Prospective Multicenter Single-Arm Staged Study to Evaluate the Plan Title: Safety and Effectiveness of EmbraceTM Hydrogel Embolic For Transcatheter Embolization of Arterial Bleeding in Solid Organs and Peripheral Arteries

99 years and younger
All genders
This is a prospective, multicenter, single arm, staged clinical study. The study is designed to assess the safety and effectiveness of Embrace Hydrogel Embolic System when used for transarterial embolization for the treatment of arterial bleeding in solid organs and the peripheral vasculature, documented on suitable radiographic and/or endoscopic imaging …
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UPCC 16122 A Phase II Multicentre Open-Label Study to Assess the Efficacy and Safety of Olaparib Monotherapy and Olaparib Plus Durvalumab Combination as Neoadjuvant Therapy in Patients with BRCA Mutations and Early Stage HER2-Negative Breast Cancer (OlympiaN)

99 years and younger
All genders
This study to learn more about olaparib and olaparib plus durvalumab combination therapy and also to better understand the studied disease, breast cancer, and associated health problems.
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UPCC 04423: Expanded Access Program for belantamab mafodotin in Patients with Relapsed/Refractory Multiple Myeloma who are Refractory to a Proteasome Inhibitor and an Immunomodulatory Agent and an Anti-CD38 Antibody

99 years and younger
All genders
Compassionate use access to belantamab mafodotin (GSK2857916) for eligible participants with refractory/relapsing multiple myeloma. We would like to rely on WCG as the IRB of record for this study.
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