Found 27 healthy volunteers trials
A listing of healthy volunteers medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
The Role of the Microbiome in Inter-Individual Variability in NSAID Disposition and Response
Phase 1
Non-steroidal anti-inflammatory drugs (NSAIDs) are commonly used in the treatment of pain and inflammation. Mounting evidence indicates that rectal administration of NSAIDs is also effective in preventing pancreatitis following endoscopic retrograde cholangiopancreatography (ERCP) by an unknown mechanism. Alterations in the salivary and fecal microbiome have been observed in patients with …
Healthy volunteers for Neuroinflammatory research study
We are conducting research studies on how immune system cells contribute to inflammatory conditions of the nervous system, such as multiple sclerosis, neuromyelitis optica (NMO), encephalitis, head injury, epilepsy, Parkinson's disease (PD), Alzheimer's disease (AzD), Lou Gherig's disease (amyotrophic lateral sclerosis; ALS) frontotemporal dementia (FTD) and others. This includes investigating …
SAGE-Purview HD
Assess magnitude of the baseline differences between participants with early Huntington's Disease & healthy participants with respect to measures of cognitive performance, evaluate effect of SAGE-718 on cognition & functioning outcomes in participants with HD & to evaluate safety & tolerability of SAGE718 in participants with HD, evaluate reliability & …
11C-M503 PET
Primary Objectives Determine biodistribution of the radioactive investigational drug, 11C M503 and calculate human dosimetry (at least 10 male and female participants). Demonstrate the feasibility of imaging the brain with the novel imaging agent 11C M503 Determine the most appropriate data analysis methodology. Determine whether there is selective uptake of …
11C-HY-2-15 PET
Primary Objectives Determine biodistribution of the radioactive investigational drug, 11C HY-2-15 and calculate human dosimetry (at least 10 male and female participants). Demonstrate the feasibility of imaging the brain with the novel imaging agent 11C HY-2-15 Determine the most appropriate data analysis methodology. Determine whether there is selective uptake of …
FDG and SGLT2 Glucose Suppression
Primary objective is to: To assess rates of complete myocardial glucose suppression (MGS) with 7 days of sotagliflozin 400 mg QD among healthy volunteers on a background of 1 day of the KD (N=20) and 3 days of the KD (N=20). Secondary objective is to: To investigate the relationship between …
Optimizing Neuromodulation through Individualized Stimulation Frequencies
Transcranial magnetic stimulation (TMS) is a non-invasive mechanism for stimulating brain regions in humans. TMS can potentiate or inhibit activity in various brain regions, and it allows researchers to exert causal control to explore and define network connectivity among brain regions. Using real-time brain readouts combined with interleaved TMS/fMRI, we …
Evaluation of Long-Axial Field-of-View Positron Emission Tomography (PET) Scanner
Normal 0 false false false EN-US X-NONE X-NONE The research study is being done to test the performance of a new type of whole-body imaging device called a Positron Emission Tomography (PET) long-axial field-of-view scanner, called the PennPET Explorer, that has been developed at the University of Pennsylvania and is …
Participate in a Birth Control Patch Research Study!
Phase 3
The Women's Health Clinical Research Center at University of Pennsylvania is currently recruiting healthy women who have regular periods and do not wish to become pregnant for at least 12 months for a research study of an investigational birth control patch. The study patch that will be used in this …
![Imaging inflammation in individuals with Alcohol Use Disorder: an [18F]NOS study](/media/img/trial_thumbnails/img/siteimg/19_y57mJN5.png)
Imaging inflammation in individuals with Alcohol Use Disorder: an [18F]NOS study
This is a research study for people ages 18-65 to learn more about how regular alcohol use affects inflammation in the brain and other organs. We will study this using a Positron Emission Tomography (PET/CT) scan using a radioactive imaging drug called [18F]NOS. [18F]NOS is an experimental radioactive molecule used …
