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Found 930 All Conditions trials

A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

A Prospective and Retrospective Multi-Centre Post-Market Non-Interventional Study of Terumo Aortic* Cardiovascular Patches and Knitted and Woven Graft

99 years and younger
All genders
A multicentre, non-interventional, post-market registry to collect safety and performance data on all commercially available knitted and woven grafts, and cardiovascular patches. Data will be collected both retrospectively and prospectively.
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Noninvasive Subharmonic Aided Pressure Estimation of Portal Hypertension

99 years and younger
All genders
Determine the reproducibility of the subharmonic aided pressure estimation (SHAPE) algorithm in subjects to estimate portal pressures with an ultrasound scanner. Examine if serial SHAPE can accurately predict development of ascites and other liver related events. Use SHAPE to monitor treatment response in patients identified with portal hypertension and compare …
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A double-blind randomized placebo-controlled study to assess the safety and efficacy of nebulized PC945 when added to systemic antifungal therapy for the treatment of refractory invasive pulmonary aspergillosis

99 years and younger
All genders
This Phase 3, double-blind, randomized, placebo-controlled, parallel-group, multi-center, international study will assess the efficacy, safety and tolerability of nebulized PC945 when added to systemic antifungal therapy for the treatment of refractory invasive pulmonary aspergillosis (IPA).
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UPCC 11222: A Phase 2 Trial to Evaluate the Safety and Efficacy of Domvanalimab (AB154) and Zimberelimab (AB122) -Based Treatment Combinations in Patients with Advanced Upper Gastrointestinal Tract Malignancies

99 years and younger
All genders
The purpose of this study is to test the safety and effectiveness of domvanalimab when given together with zimberelimab with and without chemotherapy. We would like to rely on WCG the IRB of record for this study.
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Analysis of lymphatic fluid from the thoracic duct of healthy subjects and patients with MS before and during Ofatumumab treatment

18-55 years
All genders
The overall objectives of this study are to evaluate feasibility and safety of thoracic duct sampling, including "in-and-out" cannulation and "indwelling" catheterization in early MS and to compare cellular and signaling markers in thoracic duct lymph compared to measures in the blood, within and across populations of MS patients before …
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UPCC 32922: A Phase 1 First-in-Human Study of IK-930 an Oral TEAD Inhibitor Targeting the Hippo Pathway in Subjects With Advanced Solid Tumors

99 years and younger
All genders
Phase 1
Please refer to Protocol, Section 1.1.3. (Study Objectives and Endpoints) Please refer to Protocol, Section 3. (Objectives and Endpoints) Please refer to Protocol, Section 3. (Objectives and Endpoints)
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UPCC 10122 A Randomized Open-label Phase 3 Study of Sacituzumab Govitecan and Pembrolizumab Versus Treatment of Physician's Choice and Pembrolizumab in Patients With Previously Untreated Locally Advanced Inoperable or Metastatic Triple-Negative Breast Cancer Whose Tumors Express PD-L1

99 years and younger
All genders
The primary objective of this study is to compare the progression-free survival (PFS) between sacituzumab govitecan-hziy (SG) and pembrolizumab versus treatment of physician's choice (TPC) and pembrolizumab in participants with previously untreated, locally advanced inoperable or metastatic triple-negative breast cancer, whose tumors express programmed cell death ligand 1 (PD-L1).
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Multi-center parallel-group randomized controlled trial of modified natural versus programmed cycles for frozen embryo transfers and their association with preeclampsia and live births (NatPro)

18-41 years
All genders
The primary objective is to determine the proportion of preeclampsia in pregnant women assigned to a modified natural cycle FET (corpus luteum present) protocol compared to a programmed FET (corpus luteum absent) protocol.
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UPCC 04223: Brightline-2: A Phase IIa/IIb open-label single-arm multi-centre trial of BI 907828 for treatment of patients with locally advanced / metastatic MDM2 amplified TP53 wild-type biliary tract adenocarcinoma pancreatic ductal adenocarcinoma or other selected solid tumours

99 years and younger
All genders
This study is open to adults with advanced cancer in the biliary tract, pancreas, lung, or bladder for whom previous treatment was not successful or no treatment exists, to find out whether a medicine called BI 907828 helps. BI 907828 is a so-called MDM2 inhibitor that is being developed to …
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Remote Blood Biomarker Monitoring in Frontotemporal Lobar Degeneration: Neurofilament Survillance Project (NSP)

18-85 years
All genders
This is a biomarker study designed to collect and analyze blood specimens from individuals carrying known familial frontotemporal lobar degeneration (f-FTLD) mutations compared to a control group of individuals without known f-FTLD mutations.
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