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Found 938 All Conditions trials
A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
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The purpose of this study is to see if the drugs methotrexate, azathioprine, adalimumab, infliximab, and tocilizumab are effective in treating relapsing polychondritis (RP). The study has 2 stages. Participants enrolled in the first stage of the study will receive methotrexate or azathioprine (if there is a medical contraindication to …
This study investigates below the knee arterial disease. The purpose of this study is to compare the effectiveness and safety of a sirolimus-coated balloon with standard angioplasty treatment.The study evaluates the potential benefits of using sirolimus-coated balloons, focusing on their safety and effectiveness in treating below the knee arterial disease.Who …
Primary Objective To determine the normal [18F-]FTHA transit times through the intestinal lymphatic system, and TD among healthy human subjects imaged on the PennPET Explorer (Whole body PET scanner). Secondary Objectives A. To evaluate the viability of [18F]FTHA imaging to detect and ascertain the level of lymphatic obstruction among patients …
This study is being conducted to evaluate the short and long-term outcomes of patients with severe alcohol-associated liver disease undergoing liver transplant evaluation. This study includes follow-up after liver transplant if that occurs. Participation in this study will last up to 3 years. An optional aspect of the study is …
This study investigates the use of microbiota therapy for reducing colonization with multi-drug resistant organisms in patients. The condition being focused on is the presence of these resistant organisms in individuals admitted to long-term care facilities.The study evaluates the safety and effectiveness of administering microbiota therapy to patients colonized with …
The AG10-501 ACT-EARLY study is a randomized, multicenter, double-blind, placebo-controlled study of acoramidis for prevention of ATTR. The objective of this study is to evaluate if the use of acoramidis as a prophylactic intervention in individuals who are carriers of a known pathogenic TTR variant but with no clinical evidence …
This study investigates idiopathic Multicentric Castleman Disease (iMCD).The study evaluates the effects of an investigational medication on iMCD symptoms and how well it is tolerated by participants.Who can participate: Adults aged 18 to 80 with a history of iMCD can participate. Key eligibility includes documented disease history, not responding to …
Systemic sclerosis (SSc) is a rare, chronic, autoimmune, connective tissue disease with one of the highest mortality rates among rheumatic diseases. Objective of the study is to evaluate the efficacy of efgartigimod for SC administration coformulated with rHuPH20 (efgartigimod PH20 SC) compared with placebo (placebo PH20 SC) on skin sclerosis …
This is a phase-III multi-center double-blind randomized clinical trial of 1,800 individuals with a history of prior preterm birth 35 weeks randomized to either 162 mg aspirin or 81 mg aspirin initiated between 10 and 15 weeks gestation and continued through 36 weeks gestation.
The overarching aim is to establish a quality high-density SCI repository with demographic, clinical, imaging, biomarker and outcome data suitable for data mining and research in the characterization, evaluation and prognostication of SCI. In addition, we have the following specific aims: - Examine the available evidence for a correlation between …
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