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Found 940 All Conditions trials

A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

 Upregulating action semantics to facilitate naming in aphasia
18-99 years
All genders
Phase 1
The goal of this research is to improve the likelihood of aphasia treatment success by activating brain networks that can compensate for language impairment. We will use non-invasive brain stimulation and gesture-priming paradigms to encourage activation of action knowledge (semantics), which we predict will in turn boost verb retrieval. We …
 Studying symptomatic Transthyretin Amyloid Cardiomyopathy for those who Completed the Phase 3 ATTRibute-CM Trial (AG10-301)
18-99 years
All genders
Phase 3
This open-label study is designed to evaluate the long-term safety and tolerability of acoramidis in participants with ATTR-CM, administered on a background of stable heart failure therapy. This study follows the randomized, double-blind, placebo-controlled Study AG10-301 which was designed to examine safety and efficacy in this same population.
 Potential Role of FDG-PET-CT in Assessing Cardio-Vascular-Pulmonary  CNS and Other Complications of COVID-19 Infection
18-99 years
All genders
The research study is being conducted to assess the role of Fluorodeoxyglucose (FDG)-Positron Emission Tomography (PET) imaging (a radiology scan) for monitoring the course of COVID-19 infection.
 A5128: Plan for Obtaining Informed Consent to Use Stored Human Biological Materials (HBM) for Currently Unspecified Analyses
18-99 years
All genders
Some samples (for example, blood, tissue, fluids) taken from you during this or another research study might be useful for research at some later date. This study is being done so that your samples can be stored and used at some later date for research studies, including genetic testing. These …
 Collection of Samples from the United States Population for Optimization and Evaluation of Colorectal Cancer (CRC) Plasma Circulating Free-DNA (cfDNA) Marker Panel Performance
45-85 years
All genders
This study is designed to prospectively collect blood samples and clinical data from subjects that have a suspected advanced adenoma or have been newly diagnosed with colorectal cancer and scheduled for resection surgery, and subjects who are at average risk of colorectal cancer and who are scheduled for routine colonoscopy …
 A Study Evaluating the Efficacy and Safety of Adjuvant Atezolizumab and Trastuzumab Emtansine for Participants With HER2-Positive Breast Cancer at High Risk of Recurrence
18-99 years
All genders
Phase 3
This is a study in participants with HER2-positive primary breast cancer who have received preoperative chemotherapy and HER2-directed therapy, including trastuzumab followed by surgery, with a finding of residual invasive disease in the breast and/or axillary lymph nodes
 A Study to Evaluate the Effectiveness and Safety of CAEL-101 in Patients With Mayo Stage IIIb AL Amyloidosis
18-99 years
All genders
Phase 3
Interventional
AL (or light chain) amyloidosis begins in the bone marrow where abnormal proteins misfold and create free light chains that cannot be broken down. These free light chains bind together to form amyloid fibrils that build up in the extracellular space of organs, affecting the kidneys, heart, liver, spleen, nervous …
99 years and younger
All genders
Phase 2
Compare brain fMRI response to injectable extended-release buprenorphine (Brixadi, XR-BUP) and naltrexone (XR-NTX, Vivitrol) Our primary outcome combines adherence to treatment and the frequency of illicit opioid use during treatment. The primary outcome is a binary indicator of treatment success: Participants who provide 2 weekly UDS positive for opioids or …
 ANDROMEDA-SHOCK-2 Trial
18-99 years
All genders
Septic shock is a disease of the circulatory system representing a complication of serious infections, and is associated with a very high mortality, since around 1/3 of patients with this condition die. This disease produces a series of alterations in the body, including failure of the heart, kidneys, liver, among …
 Safety and Efficacy Study of Ravulizumab in Adults With Generalized Myasthenia Gravis
18-99 years
All genders
Phase 3
Interventional
The primary purpose of this study is to evaluate the safety and efficacy of ravulizumab for the treatment of participants with generalized myasthenia gravis (gMG).
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