Found 938 All Conditions trials
A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
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The primary objective of this study is to determine if treatment of the femoral head with core decompression and cell grafting increases the survivorship of the hip when compared to core decompression alone. The secondary objectives are to determine which factors may contribute to the success or failure of these …
Objective 1: Estimate efficacy of medical management with oral letrozole 10 mg daily for three consecutive days followed by vaginal misoprostol 800 mcg for treatment of EPL Objective 2: Assess side effects, adverse events, and patient acceptability associated with letrozole and misoprostol for medical management of EPL Our primary outcome …
The goal of the SAK study is to test whether Empagliflozin, with and without Potassium Nitrate, improves submaximal exercise endurance and skeletal muscle oxidative phosphorylation capacity in participants with Heart Failure with Preserved Ejection Fraction. We are assessing whether this medication and supplement, either together or separate, helps relieve symptoms …
This is a prospective, open-label, multi-center, single-arm study enrolling subjects with severe heterogeneous emphysema and collateral ventilation in the target lobe. Subjects will undergo instillation of AeriSeal Foam in the target lobe and subsequent assessment CV status using Chartis Pulmonary Assessment System. Subjects with CV- status will then undergo placement …
The study will investigate 20 mg seltorexant as adjunctive treatment to SSRI/SNRI antidepressants for major depressive disorder (MDD) compared with placebo as adjunctive therapy in patients with a partial response to first line antidepressant therapy.
The purpose of this research study is to better understand anxiety fluctuations during the perinatal period using technology-based daily assessment of mood, anxiety, sleep, and activity levels. This study uses a daily mood diary to monitor anxiety and wearable technology to track sleep and physical activity. All tasks during the 28-day …
This is a phase 3 trial of AOC 1001, an antibody-oligonucleotide conjugate. Protocol includes participants ages 16-65 with a clinical and genetic diagnosis of DM1 with DMPK CTG repeat length greater than or equal to 100; Penn site will enroll ages 18 to 65 years only. Participants will be randomized …
If you are struggling with illicit fentanyl use, a new clinical research study is available for you. The purpose of this research study is to determine whether a new approach to starting buprenorphine ("Suboxone") has less withdrawal than the standard approach. This new approach is called rapid low dose initiation. Another …
This study investigates cystic fibrosis (CF) in individuals who do not take cystic fibrosis transmembrane conductance regulator (CFTR) modulators. The purpose of this study is to collect health data and specimens to support the development of treatments for people with CF who are not using CFTR modulators.Participants will be part …
To assess safety and tolerability, including dose-limiting toxicities (DLTs), maximum tolerated dose (MTD), or maximum administered dose (MAD; if no MTD is defined) of IMGN151 when administered intravenouslyTo determine recommended Phase 2 dose (RP2D) for IMGN151To characterize the pharmacokinetics (PK) and immunogenicity of IMGN151 -To assess ORR for IMGN151 using …
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