Found 12 Parkinson's disease trials
A listing of Parkinson's disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
Phase 1
This is a 5 year study and the purpose is to assess the safety and tolerability of 2 dose levels of PR001A administered via l injection in patients with moderate to severe Parkinson's Disease
The LRRK2protein may contribute to disease progression in patients with PD.The study drug (BIIB122) is designed to affect the activity of LRRK2 protein in the brain and may prevent or delay the development of PD symptoms.The main purpose of this study is to look at whether the study drug works …
Phase 2
The study is designed to evaluate the efficacy and safety of intraputaminal delivery of AAV2-GDNF gene therapy in subjects with moderate Parkinson's disease and demonstrate proof-of-concept. Subjects will be randomized to 1 of 2 treatment arms, AAV2-GDNF surgery or control surgery and will undergo screening, two baseline visits, perioperative procedures, …
Subjects currently enrolled in the PD0053 can be enrolled in this study. Subjects will take UCB0599 capsules twice a day at either 180 mg or 360 mg approximately 12 hours apart. The start of the study will overlap with the end of the parent study and run for 30 months …
The purpose of this study is to gain a better understanding of how signals in the brain contribute to abnormal sleep behavior in patients with Parkinson's Disease (PD).
Non-Invasive Brainstem Modulation for the Treatment of Non-Motor Symptoms in Parkinsons Disease: A Randomized Controlled Trial (RCT) and an Open Label Extension (OLE) Study
The purpose of this study is to continue to obtain information from people with and without Parkinson disease (PD) so that researchers may better understand how Parkinson disease progresses, in order to inform better treatments. The information collected in this study is for research and not for clinical care. This …
The purpose of this study is to look at racial disparities in people with Parkinsons Disease (PD) by studying symptoms and signs, management, and genes in Black PD patients compared to a group of White PD patients.
We are conducting research studies on how immune system cells contribute to inflammatory conditions of the nervous system, such as multiple sclerosis, neuromyelitis optica (NMO), encephalitis, head injury, epilepsy, Parkinson's disease (PD), Alzheimer's disease (AzD), Lou Gherig's disease (amyotrophic lateral sclerosis; ALS) frontotemporal dementia (FTD) and others. This includes investigating …
The objective of this study is to determine whether visual pathway structure and function correlates with hallucination severity and treatment outcomes in Parkinson disease. The primary outcome variable is hallucination severity, which will be quantified using the PD-adapted Scale for the Assessment of Positive Symptoms (SAPS-PD), a standardized semi-structured instrument …
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