ProCAN | Clinical Research Studies Listing

Recruiting

17 years - 30 years

All

Phase 1

1 Location

Brief description of study

A Phase Ib, randomized, double-blind, placebo-controlled, multi-center, study designed to investigate the responsiveness of a range of cognitive, clinical, biological and digital biomarkers in the CHR population, following 8-weeks of twice-daily oral dosing. The primary focus is to investigate how the selected biomarkers respond to MT1988.

Detailed description of study

The purpose of this study is to see if certain cognition, biological, cell-phone, and clinical health markers will show changes for those taking MT1988 compared to placebo, and to see how safe and tolerable MT1988 is compared to a placebo.

MT1988 is a product that combines two drugs approved for clinical use in the US or other countries. Only a limited number of people have taken both together, but no serious problems with combining them occurred.

Study Procedures
The main procedures in the study include:

Interviews and cognitive tasks
Study drug tablets taken daily
Physical assessments
Electroencephalogram (EEG)
Blood samples and Genetic testing
Digital assessments

Some of the interviews will be audio recorded.

Length of Participation
Your participation is expected to last about 4 months and includes 10 visits, some of which are expected to last a full day.

Compensation
You will be paid for your time in this study. You will also be reimbursed for any travel expenses per visit.

Eligibility of study

You may be eligible for this study if you meet the following criteria:

Conditions: Medical Research
Age: 17 years - 30 years
Gender: All

You are being asked to participate in this project because you have recently been experiencing changes in your mood, thinking, or behavior which may indicate you are an individual who is at risk for psychosis.

Updated on 02 Apr 2026. Study ID: 25-1605

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