UPCC 22923 Assessing genetic testing preferences for CDH1 and TP53 amongst patients undergoing cancer genetic testing

Enrolling By Invitation
99 years or below
All
Phase N/A
2000 participants needed
1 Location

Brief description of study

The overall objectives of this study are to quantify the proportion of patients who opt in to testing for the genes CDH1 and TP53 on multigene panel testing as well as those who decline testing for these genes, and determine factors that may be predictive of who does and does not agree to include these genes on their genetic testing panels. The primary outcome variable of this study is the proportion of Cancer Genetics Risk Evaluation Program patients who wish to include the genes CDH1 & TP53 on multi-gene panel testing for cancer predisposition syndromes. The secondary outcome variables of this study are the reasons why people forego CDH1 & TP53 testing on multi-gene panel testing for cancer predisposition syndromes (which are recorded in genetic counseling notes as part of routine standard-of-care) and demographic and other personal factors that are predictive of forgoing testing for these genes.

Eligibility of study

You may be eligible for this study if you meet the following criteria:

  • Conditions: Medical Research
  • Age: 99 years or below
  • Gender: All

TBD

Updated on 22 Apr 2026. Study ID: 23-0599
If you need assistance finding a non-cancer clinical research study or if you have any questions, please email psom-ocr@pobox.upenn.edu For Cancer trials contact Penn Medicine's Cancer Trial Navigator at: PMCancerResearch@pennmedicine.upenn.edu or 215-349-8245

Study is selecting its participants from a population, or group of people, decided on by the researchers in advance.

Contact Abramson Cancer Center Navigator