Reward, Salience, and Value Processing in Youths at | Clinical Research Studies Listing

Reward, Salience, and Value Processing in Youths at Risk for Psychosis: The RSVP Study

Recruiting

16 years - 35 years

All

Phase N/A

88 participants needed

1 Location

Brief description of study

The Reward, Salience, and Value Processing in At-risk Youth (RSVP) study is recruiting young people who are concerned about the possibility of developing psychosis.

Detailed description of study

What is the purpose of this study?

Mental illness affects many individuals and often begins to develop in adolescence or young adulthood. The primary purpose of this study is to:

Improve the ability to identify youth at-risk of developing psychosis
Better understand why some young people develop psychosis and others do not

This research project aims to increase understanding of mental health concerns in young people and how to prevent the development of a more serious mental
illness.

What Would I Do?

You would first meet with the study staff for an interview to determine if you are eligible for the study. You would then complete several assessments, including:

Clinical Interview: The clinical interview focuses on questions about your daily life, such as your friendships and school or work, and about different
experiences and symptoms.
Cognitive Testing and Magnetic Resonance Imaging (MRI): These assessments focus on memory, attention, concentration and learning.

Eligibility of study

You may be eligible for this study if you meet the following criteria:

Conditions: Psychosis Risk
Age: 16 years - 35 years
Gender: All

Some individuals may be at higher risk of developing psychosis than others. This study is recruiting people who have experiences or circumstances that may put them at higher risk.

You may be eligible for this study if you meet the following criteria:

Ages 16-35
Noticing a recent change in thinking, behavior, or experiences, such as:
Confusion about what is real or imaginary
Feeling not in control of your own thoughts of ideas
Feeling suspicious or paranoid
Having experiences that may not be real, such as hearing sounds or seeing things that may not be there
Having trouble communicating clearly

Most people who have these symptoms do not go on to develop psychosis. We are trying to understand why some people have these experiences do develop psychosis while many others do not.

Updated on 17 Jul 2025. Study ID: 24-0568

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