UPCC 11023 The Role of Flavor in the | Clinical Research Studies Listing

Recruiting

21 years - 100 years

All

Phase N/A

246 participants needed

1 Location

Brief description of study

The purpose of this study is to investigate whether smokers who have been unable to quit with traditional approaches can switch to e-cigarettes and if flavor affects the ability to switch.

Detailed description of study

This research study is being conducted to examine whether e-cigarette flavors affect the ability to switch from combustible cigarettes to e-cigarettes. During the study, participants will be randomly assigned to one of three flavors: menthol, tobacco, or fruit e-cigarettes. Participants will be provided with the e-cigarette and pods of their assigned flavor (at no cost) and be instructed to use them across 6 weeks. The entire study consists of 9 in-person sessions at our Center over the course of 7 weeks (about 1 visit/week) plus 1 follow-up visit 6-months after switching to e-cigarettes.

The first 3 visits will take approximately 1-2 hours to complete, and the remaining sessions will take about 15-30 minutes.

Participants will be asked to:

Provide breath samples.
Provide urine samples.
Meet with a quit-smoking counselor to create a plan for switching to e-cigarettes.
Complete computer tasks and questionnaires about smoking behavior and other smoking-related topics.
Use the e-cigarette in our Center’s well-ventilated smoking room.
Collect and return all used cigarette filters and pods in date-stamped baggies provided by the Center.

Eligibility of study

You may be eligible for this study if you meet the following criteria:

Conditions: Smoking, Cigarette, Quit Smoking
Age: 21 years - 100 years
Gender: All

Updated on 08 Oct 2025. Study ID: 23-1006

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