SCD Depo
Brief description of study
To assess prospectively the frequency of acute vaso-occlusive episodes (VOEs) and VOE-associated biomarkers. The secondary outcome is VOE-related biomarker levels during each phase. During both the baseline and intervention study phases, participants will provide weekly reports via electronic survey of vaso-occlusive pain. VOE will be defined as self-reported typical SCD pain that interferes with usual daily activities or requires emergency care or hospitalization, with distinct episodes separated by at least 2 weeks without pain. Cellular blood counts, clinical chemistries, inflammatory cytokines, coagulation markers, and markers of cellular activation will be measured from blood samples drawn twice during each study phase.
Eligibility of study
You may be eligible for this study if you meet the following criteria:
- Conditions: Medical Research
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Age: - 99 Years
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Gender: All
TBD
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