Profiling Asthma Immune Responses to Improve Therapeutics (PAIR-IT) (PAIR-IT)

Enrolling By Invitation
18 years - 99 years
All
Phase N/A
60 participants needed
1 Location

Brief description of study

Researchers at the University of Pennsylvania in the Department of Biostatistics, Epidemiology and Informatics and the Division of Pulmonary, Allergy, and Critical Care Medicine are conducting a study to better understand how blood immune cells, which are involved in allergies and asthma, change in asthma patients who take asthma biologic drugs. Understanding these blood immune cell changes may help us understand who will best respond to biologic drugs.   

Detailed description of study

If you agree to join the study, the care you receive will not change. Your physician will choose the type of biologic drug and dose in accordance with current clinical guidelines and what they think will be most helpful to you. If you join, you will be asked to:

•Complete a blood draw and questionnaire before you come in for your first biologic injection

•Complete another blood draw and questionnaire after one month of your first biologic injection

•After each visit, you will be paid $50

Eligibility of study

You may be eligible for this study if you meet the following criteria:

  • Conditions: Medical Research
  • Age: 18 years - 99 years
  • Gender: All

You may be eligible for this study if you are 18 years or older and:

•You have severe asthma

•A Penn Medicine asthma specialist has prescribed one of the following biologics to you:

-Dupixent (Dupilumab)

-Nucala (Mepolizumab)

-Xolair (Omalizumab)

-Tezspire (Tezepelumab)

 

Updated on 30 Apr 2026. Study ID: 24-0510
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Study is selecting its participants from a population, or group of people, decided on by the researchers in advance.

Contact Office of Clinical Research