Delphi-MD TMS EEG TBI Study
Brief description of study
To assess TMS-EEG abilities to aid in diagnosis, prognosis, and classification of TBI patients and predictions of clinical outcomes as well as to assess Delphi-MD abilities in the classification of TBI injury in comparison to standard brain measures. Differentiating between healthy controls and TBI participants in measured outputs of the Delphi-MD device (WFA, STP, EPD, LPD, and connectivity) Correlating Delphi-MD outputs with neural deficits identified through patient reported and clinician reported outcome measures. The following functional outcome and symptom measures will be obtained as primary outcomes in all groups: Glasgow Outcomes Scale-Extended (GOSE), Brief Symptom Inventory-18 (BSI-18), Rivermead Post-Concussion Symptom Questionnare (RPQ), Satisfaction with Life Scale (SWLS). TMS-EEG outputs will differ between TBI subjects with high symptom burden and those with low symptom burden (defined by RPQ and BSI-18). TMS-EEG outputs will correlate with MRI measures of axonal integrity (White matter fractional anisotrophy (FA) on DTI-MRI). While MRI is not a requirement for this study, we expect that a substantial subset of participants in this study will be co-enrolled in other MRI studies at out center.
Eligibility of study
You may be eligible for this study if you meet the following criteria:
- Conditions: Medical Research
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Age: 99 years or below
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Gender: All
TBD
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