NOTCH Study
Brief description of study
Notch signaling plays a key role in regulating stem cell differentiation in the GI tract, with increased Notch activity promoting absorptive lineage differentiation, and Notch inhibition resulting in secretory lineage differentiation including goblet cells, the hallmark of esophageal intestinal metaplasia. Notch may be particularly relevant to BE and progression to EAC, as demonstrated by our extensive data that increased Notch activity drives progression to EAC .
Eligibility of study
You may be eligible for this study if you meet the following criteria:
- Conditions: Medical Research
-
Age: - 99 Years
-
Gender: All
TBD
Find a site
,
You have contacted , on
Your message has been sent to the study team at ,
What happens next?
- You can expect the study team to contact you via email or phone in the next few days.
- Sign up as volunteer to help accelerate the development of new treatments and to get notified about similar trials.
You are contacting
