UPCC 04823 Intravesical Treatment of Bladder Cancer at Home, Multi-modal Treatment Support (BCG at Home)

Investigational Study on Home-based Bladder Cancer Treatment

Enrolling By Invitation
18 years or above
All
Phase N/A
50 participants needed
1 Location

Brief description of study

The proposed project will have two separate cohorts. The first will be to perform a more in-depth qualitative assessment of the barriers and facilitators for treatment compliance for non-muscle invasive bladder cancer. The second arm will be to create and test a BCG at home program. Participants in the second cohort will be enrolled in a conversational agent to measure patient symptoms and quality of life and improve self-efficacy.

Detailed description of study

The proposed project will have two separate cohorts. The first will be to perform a more in-depth qualitative assessment of the barriers and facilitators for treatment compliance for non-muscle invasive bladder cancer. The second arm will be to create and test a BCG at home program. Participants in the second cohort will be enrolled in a conversational agent to measure patient symptoms and quality of life and improve self-efficacy.

Eligibility of study

You may be eligible for this study if you meet the following criteria:

  • Conditions: Bladder Cancer
  • Age: 18 years or above
  • Gender: All

Inclusion Criteria:

Inclusion criteria for patients in Cohort 1

  • Age 18 years or older;
  • completed intravesical treatment for non-muscle invasive bladder cancer within the past year Cohort 1 inclusion criteria for key stakeholders
  • Age 18 years or older;
  • experience with the delivery of BCG delivery for more than 2 years

Cohort 2 inclusion criteria

  • Age 18 years or older;
  • diagnosed with non-muscle invasive bladder cancer and prescribed BCG for initial therapy

Exclusion Criteria:

Cohort 1 exclusion criteria

• inability to provide informed consent

Cohort 2 exclusion criteria

  • inability to provide informed consent
  • inability to undergo catheterization (i.e. - history of urethral stricture)
  • inability to receive BCG therapy (i.e. - previous reaction with BCG)
  • no access to mobile phone
  • inability to respond to written conversations in English

This study investigates the treatment of non-muscle invasive bladder cancer. The purpose of this study is to explore the barriers and facilitators affecting treatment compliance and to test a Bacillus Calmette-Guerin (BCG) at-home program. Participants will be divided into two study arms: one focusing on understanding treatment compliance and the other testing the home-based BCG treatment program.

Participants in the second study arm will receive BCG treatment at home and will use a conversational agent. This agent will help measure their symptoms, quality of life, and improve their ability to manage their own health. The study will collect information to better understand how patients manage their treatment and any challenges they face.

  • Who can participate: Adults aged 18 years or older who have completed intravesical treatment for non-muscle invasive bladder cancer within the past year or who have been diagnosed with the condition and prescribed BCG for initial therapy can participate. Key stakeholders with over 2 years of experience in BCG delivery are also eligible.
  • Study details: Participants will either engage in discussions to identify barriers to treatment or receive investigational BCG therapy at home while using a conversational agent to report symptoms and quality of life.
Updated on 28 Jul 2026. Study ID: 23-0460
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