Dosing of LT4 (DOT4)

Recruiting

65-100 years

All

Phase N/A

228 participants needed

1 Location

Brief description of study

The purpose of this study is to find the effects of taking different doses of the thyroid medication levothyroxine in older people who already take levothyroxine for hypothyroidism.

Older people are more likely to have problems when their dose of levothyroxine is too strong. Allowing lower doses of levothyroxine would help prevent overmedicating older people with levothyroxine doses that are too strong.

Detailed description of study

The study involves 3 in person visits at Penn Research Center, 4 or 5 visits to your local Penn lab, and receiving 4 phone calls from study staff over approximately 8 to 10 months.

Eligibility of study

You may be eligible for this study if you meet the following criteria:

Conditions: Endocrinology,Diabetes,Metabolism,EDM
Age: Between 65 Years - 100 Years
Gender: All

Inclusion

Adult 65 years or older, not in a nursing home
Hypothyroid (any type) for at least 6 months
Currently taking 75-200 mcg of levothyroxine (under any brand name) per day
Willing to adhere to study levothyroxine medication regimen

Exclusion

Currently taking liothyronine (LT3) or thyroid extracts
Currently taking amiodarone

Updated on 01 Aug 2024. Study ID: 853300

Pre-Screener

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