MRI and Biological Markers of Acute E-Cigarette Exposure in Smokers and Vapers

MRI and Biological Markers of Acute E-Cigarette Exposure in Smokers and Vapers
Recruiting
18-45 years
All
Phase N/A
64 participants needed
1 Location

Brief description of study

This research study is being conducted to examine the effects of electronic cigarette aerosol, in the presence and absence of nicotine, on the endothelium, a layer of cells that act as a protective barrier and play an important part in controlling the flow of blood around the body.

Detailed description of study

Smokers and vapers: This group will complete three study visits. During each visit blood is drawn twice, an MRI is performed twice, and a smoking challenge is completed. No more than 30, and no fewer than 3 days can pass between each visit. A parking voucher and monetary compensation will be provided for each visit ($150 for every visit completed, $450 in total). 

Nonsmokers: This group will complete one study visit during which blood is drawn once, one MRI is performed, and a hematocrit measurement is taken. A parking voucher and monetary compensation will be provided ($100 for one visit).

Eligibility of study

You may be eligible for this study if you meet the following criteria:

  • Conditions: vapers,smokers,non-smokers,vape,cigarettes,smoking
  • Age: Between 18 Years - 45 Years
  • Gender: All

Smokers, vapers, and nonsmokers with no symptomatic cardiovascular or pulmonary disorders, and a body mass index between 18.5 and 30. Potential subjects will be asked to complete a brief eligibility screening. This consists of a phone call with a study coordinator.

Updated on 01 Aug 2024. Study ID: 850432

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