A Phase 1 Study of IL-15 Superagonist (N-803) and Broadly Neutralizing Antibodies to Induce HIV-1 Control

A Phase 1 Study of IL-15 Superagonist (N-803) and Broadly Neutralizing Antibodies to Induce HIV-1 Control
Recruiting
18-70 years
All
Phase 1
3 participants needed
1 Location

Brief description of study

This study will investigate whether N-803, a new experimental drug that stimulates the immune system, is safe and tolerable when given alone and in combination with two new experimental drugs that are antibodies (natural proteins that the body makes in response to an infection) to HIV (the virus that causes AIDS), VRC07-523LS and 10-1074.

Detailed description of study

Study duration: 100-112 weeks



Additional Information
Participants must be willing to participate in analytic treatment interruption (ATI) 

Eligibility of study

You may be eligible for this study if you meet the following criteria:

  • Conditions: HIV,antiretroviral,analytic treatment interruption
  • Age: Between 18 Years - 70 Years
  • Gender: All

Individuals living with HIV on ART with a viral load <50 copies/mL for at least 96 weeks. 

Lowest CD4 count > 200 cells/mm3 

Updated on 01 Aug 2024. Study ID: 848907

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