The purpose of this protocol is to monitor the rate of recurrence in patients who undergo cancer surgery. Patient diagnosed with solid tumor cancers have a high rate of recurrence when surgery is a treatment. The high rates of recurrence suggest that surgeons are unable to completely detect and remove primary tumor nodules in a satisfactory manner as well as lingering metastases in sentinel lymph nodes. There is some data to suggest that near infrared imaging can can improve on negative margins. Patients with a diagnosis of any resectable solid tumor, including but not limited to lung nodule, breast, kidney, parathyroid, mediastinal, skin mass, soft tissue, prostate, stomach pleural, head and neck, and are at risk for local recurrence as determined by pre-operative assessment at an office in the University of Pennsylvania Heath System will be included.

You may be eligible for this study if you meet the following criteria:

• Conditions: Solid Tumors
• Age: Between 18 Years - 99 Years
• Gender: All