Matching Perfusion and Metabolic Activity in HFpEF

Recruiting

18-99 years

All

Phase 2

53 participants needed

1 Location

Brief description of study

This study will test whether Potassium Nitrate (KNO3), with and without Propionyl-L-Carnitine (PLC) and Nicotinamide Riboside (NR), improves submaximal exercise endurance and skeletal muscle oxidative phosphorylation capacity (SkM OxPhos) in participants with Heart Failure with Preserved Ejection Fraction (HFpEF). This study will also test whether the response to supplemental oxygen identifies HFpEF individuals who derive additional benefit from the other drugs as opposed to KNO3 alone.

Eligibility of study

You may be eligible for this study if you meet the following criteria:

Conditions:
Heart Failure, Preserved Ejection Fraction
Age: Between 18 Years - 99 Years
Gender: All

Updated on 30 Sep 2024. Study ID: 844627

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