The purpose of this study is to characterize gene mutations associated Central Centrifugal Cicatricial Alopecia (CCCA). The Penn Medicine BioBank (PMBB) supports researchers by providing centralized access to a large number of annotated blood and tissue samples. Clinician identified patients with CCCA and appropriate controls will be recruited from the dermatology outpatient clinics of Penn Medicine and invited to participate in the study. Their blood samples will be obtained and stored in the BioBank. Finally, a control group of non-scarring hair loss patients who have specimens in the PMBB will be identified as well as new control subjects. The blood will be analyzed for DNA mutations. A simple questionnaire will be used to prescreen subjects to identify patients and their families who may have alopecia.

You may be eligible for this study if you meet the following criteria:

• Conditions: alopecia,hair loss
• Age: - 99 Years
• Gender: All