Effects of Nutritional Ketone Ester on Brain Function and Alcohol Consumption in Alcohol Use Disorder
Not Recruiting
21 years - 65 years
All
Phase
N/A
30 participants needed
1 Location
Brief description of study
The goal of this study is to learn more about how a nutritional supplement “ketone ester” (DeltaG) has an effect on brain function and on alcohol consumption in individuals with alcohol use disorder. We will study this using Magnetic Resonance Imaging (MRI) scans.
Participants
will be compensated/reimbursed for their time and effort. Participants may be
compensated up to $677 if they complete the main study and the sub-study.
Detailed description of study
The research team is currently seeking 2 groups of
participants: drinkers and non-drinkers (control group). Please review the
criteria for participation listed in the Additional Information section, before
contacting the research team.
- Group 1: 20 participants with alcohol use disorder
- Group 2: 10 non-drinkers or healthy
controls.
Participants
that agree and qualify to join the study, will be asked to complete the
following research procedures:
- Drinking a nutritional supplement ketone ester
- MRI scans of the brain
- Blood draws for measurements of glucose or other testing
- Alcohol consumption: we will give you a tray with alcoholic drinks (i.e., vodka mixed with diet soda of your choice) Participants will be asked to come to Penn Medicine 3 times over a period of approximately 4 weeks.
Eligibility of study
You may be eligible for this study if you meet the following criteria:
- Conditions: addictions,alcohol,alcohol use disorder
-
Age: 21 years - 65 years
-
Gender: All
Updated on
01 Aug 2024.
Study ID: 844235
