ASSESSING THE HIV-1 VIRAL RESERVOIR IN TISSUE SAMPLES
Administratively Closed
18 years - 99 years
All
Phase
N/A
100 participants needed
1 Location
Brief description of study
Treating
HIV infection with antiretroviral therapy (ART) leads to control of the virus
and improvement of the immune system, which is your body natural ability to
fight diseases.
HIV patients who
are well controlled (undetectable HIV by blood tests) still have HIV virus
which hides deep in their body’s tissues (HIV reservoir) and is not completely
eliminated. The purpose of this study is to better understand the nature of
this HIV reservoir and to study strategies to eliminate it in the laboratory.
Detailed description of study
If you agree to
join the study, there
will be two visits at Penn Presbyterian Medical Center or Perelman Center for
Advance Medicine (PCAM). During the first visit we will discuss the study in
detail prior to signing the study consent.
Information will be collected about your medical history (your current medical
conditions, medications, and lab results) in order to evaluate whether you can safely
participate in this tissue collection study.
At the second study visit tissue samples from your rectal mucosa (the
lining of your gut) will be collected via a rectal biopsy by a specially
trained doctor. The rectal biopsy
procedure is performed without sedation and is generally well tolerated by
participants. Your study participation
will last over a period of approximately 1 month. You will be compensated for
each study visit.
Eligibility of study
You may be eligible for this study if you meet the following criteria:
- Conditions: HIV
-
Age: 18 years - 99 years
-
Gender: All
Updated on
05 Dec 2024.
Study ID: 834367
