We propose a prospective longitudinal cohort of radiation therapy cardiotoxicity in in patients with locally advanced non-small cell lung cancer treated with definitive chemoradiation. We will enroll patients prior to start of chemoradiation and follow them with echocardiogram, PET/CT stress test, blood draw, and symptoms/activity surveys for 2 years to determine if radiation therapy results in early, sub-clinical cardiovascular dysfunction, to understand how cardiac dose-volume parameters influence these abnormalities, and to develop multi-marker strategies in risk prediction.

You may be eligible for this study if you meet the following criteria:

• Conditions: Lung Cancer
• Age: 99 years or below
• Gender: All