Glucose is a major energy source for brain cells. Changes in blood glucose also leads to changes in supply or availability of glucose to brain cells. Changes in various brain metabolites when mapped in different areas of the brain will allow, an understanding of the effects of such changes in brain function in healthy persons. After glucose consumption MRI methods will be used to see the changes in key metabolites in brain. Healthy, normal subjects will be recruited for this study. subjects with any chronic disease or have gone through any major procedures will not be included. Either unlabeled glucose or D2-glucose will be given by oral route in about 250 ml water. MRI will last for 90 minutes. Contrast agents will not be used in this procedure.

You may be eligible for this study if you meet the following criteria:

• Conditions: metabolism
• Age: - 99 Years
• Gender: All