Clinical Core Alzheimer's Disease Core Center (ABC)
Brief description of study
The study is at the Penn Memory Center at the University of Pennsylvania and is under the direction of David Wolk, M.D.. We are currently recruiting normal control participants ages 75 years and older. The purpose of this study is to collect, store and analyze cognitive data and biological samples, such as blood and MRI imaging, from individuals without symptoms of memory loss and/or dementia. Our goal is to improve our understanding of age-associated brain changes and our ability to diagnosis and treat brain diseases. You may be asked to participate in other imaging protocols.
Detailed description of study
Recruitment of subjects is accomplished by identifying cognitively normal individuals. STUDY PROCEDURES: If you are eligible and agree to participate in this study you will give a medical history, and have a physical and neurological exam. This will include a description of any medical problems you have now, or have had in the past, a list of medications you are currently taking (including non-prescription medications and vitamins). Information will also be obtained from a person (study partner) whom you designate to speak for you and who knows you well. the study partner is required for every annual visit. In addition, the study partner may be asked to complete some assessments and questionnaires . You will have a 40 to 60 minute paper and pencil test, which will assess your memory, thinking and other problem-solving abilities. You will return once a year for a re-evaluation. During your return visits, you will report any health related changes that have occurred since your last examination. In addition, you will have a follow up physical and neurological exam and repeat the 40 to 60 minute paper and pencil test. In addition, health information will be obtained from your designated study partner during each annual visit.
Additional Information
You will be compensated for your participation in the ABC, formally the NACC study. You will receive $20 for each study annual visit and $50.00 for each MRI. You will be compensated via Greenphire re-loadable gift card.
Eligibility of study
You may be eligible for this study if you meet the following criteria:
- Conditions: Normal Controls
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Age: Between 75 Years - 100 Years
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Gender: All
