Autism Spectrum Program of Excellence | Clinical Research Studies Listing

Recruiting

3 years - 99 years

All

Phase N/A

500 participants needed

1 Location

Brief description of study

The goal of the ASPE study is to investigate the genetic basis of autism spectrum disorder (ASD) and autism-related traits.

Individuals 3 years old or older with a diagnosis (or suspected diagnosis) of autism spectrum disorder without intellectual disability, or with a deletion/duplication in the NRXN1 gene (2p16.3 deletion) and their family members, or people who are not on the autism spectrum to act as our control (comparison) may be eligible to participate.

Currently, the ASPE Study has paused enrollment for all groups except for those with a deletion/duplication in the NRXN1 gene (2p16.3 deletion) and their family members.

If you have a variant in the NRXN1 gene and would like to participate, or
If you are are eligible for one of the other groups and are interested in being placed on a wait list for when recruitment re-opens

Then you can click the link below related to your age, or you can email a member of the study team at aspe@pennmedicine.upenn.edu to learn how you can join the ASPE Study's growing community today!

Adult: https://redcap.link/aspe

Adolescent (16-17): https://redcap.link/aspe_adolescent

Child (3-15): https://redcap.link/aspe_child

Detailed description of study

Participation includes:

- Completing a series of online questionnaires

- Returning a free saliva kit for DNA analysis

- Option to wear a research grade (FitBit-like) device to track activity and sleep

- All completed in the comfort of your own home!

Eligible individuals who enroll and complete all questionnaires and provide a genetic sample will be compensated $50 for participating.

You do not need to be located in the Philadelphia area to participate. All participation can be completed from the comfort of your home.

For Additional Information

Visit our website:

https://aspe.med.upenn.edu

Or contact a member of the study team at aspe@pennmedicine.upenn.edu to learn more!

Eligibility of study

You may be eligible for this study if you meet the following criteria:

Conditions: Autism,Aspergers,ASD,AS,NRXN1,Autism spectrum disorder,2p16.3 deletion
Age: 3 years - 99 years
Gender: All

Individuals with an autism diagnosis or suspected autism diagnosis
Individuals with a Chromosome 2p16.3 deletion / NRXN1 gene deletion and their family members
People who are not on the autism spectrum (no diagnosis and no suspected diagnosis)

Updated on 29 May 2026. Study ID: 17-0012

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