T-Cell Response to Vaccination

T-Cell Response to Vaccination
Recruiting
50 years - 100 years
All
Phase N/A
1 Location

Brief description of study

The purpose of this study is to see how your body forms a protective response after vaccination and how it deals with viral variants. We are studying the immune responses to the COVID-19 vaccines. 

Detailed description of study

The study consists of a screening visit followed by other study visits. From the time of screening, you will be in this study for around 9 months.
 
You may be eligible if you plan to receive the vaccine (initial or booster) but have not yet gotten it yet. 
 
The COVID-19 vaccination study includes: a screening visit (approx 1 hour) to check your eligibility. If you qualify, you will come in for the following study visits: Study Visit 1 - Pre-Donor Evaluation (30 min) and Leukopheresis (approx 2.5-4 hours), Visit 2 – vaccination at your place of choice. The study team will not be providing the vaccine. Study Visits 3 - 8 - Blood Draws (approx 30 mins), Study Visit 9 - Leukopheresis (approx 2.5-4 hours). 
 
 
There are additional optional procedures that you may choose to participate in. These include fine needle aspiration (FNA) of the lymph nodes under your armpit to see how protective antibodies are being generated. You may also choose to participate in periodic blood draws/leukopheresis to see how immune protection holds up over the long-term.
 

Additional Information

Compensation is provided after the screening visit if eligible for the study.

Eligibility of study

You may be eligible for this study if you meet the following criteria:

  • Conditions: healthy Volunteers,healthy subjects,Healthy,Healthy volunteer,healthy,healthy volunteer,healthy volunteers,healthy subjects, autoimmunity, autoimmune disease,COVID-19,coronavirus,covid,vaccine,vaccination,covid-19,covid-19 vaccinations
  • Age: 50 years - 100 years
  • Gender: All

Must be receiving a COVID-19 vaccines or booster

Must be willing to consent to blood draws 

Updated on 06 May 2025. Study ID: 14-0115

Pre-Screener

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