Found 18 Liver Disease trials
A listing of Liver Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
Familial lecithin:cholesterol acyl transferase (LCAT) deficiency (FLD) is a rare, hereditary disease with no treatment. It is caused by mutations in the gene for LCAT, an enzyme that is made in the liver and plays a role in the body’s ability to process (“metabolize”) cholesterol. People with FLD have very …
For subjects age 18 years and older who are at an increased risk for HCC and for whom HCC surveillance is appropriate, including subjects with cirrhosis or non-cirrhotic subjects with Hepatitis B. Approximately 3,000 subjects are expected to be enrolled, comprised of approximately 2,222 ultrasound surveillance subjects and 778 subjects …
The main purpose of this study is to determine if certain genes, hormones, or other factors predict the risk of developing lung vessel disease in patients with liver disease and whether they determine outcome. Patients in need of a liver transplant evaluation or have portopulmonary hypertension or are suspected of …
AL (or light chain) amyloidosis begins in the bone marrow where abnormal proteins misfold and create free light chains that cannot be broken down. These free light chains bind together to form amyloid fibrils that build up in the extracellular space of organs, affecting the kidneys, heart, liver, spleen, nervous …
Septic shock is a disease of the circulatory system representing a complication of serious infections, and is associated with a very high mortality, since around 1/3 of patients with this condition die. This disease produces a series of alterations in the body, including failure of the heart, kidneys, liver, among …
The purpose of this study is to evaluate the outcomes of liver transplant when the donor is placed on a normothermic perfusion machine prior to donation of the liver. The perfusion machine restores oxygenated blood flow to organs in the abdomen such as the liver. The use of the machine …
This is a Phase Ib/II study in participants with advanced liver cancers. Cohort 1 - participants with locally advanced or metastatic hepatocellular carcinoma (HCC) who have not received prior systemic therapy for their disease. Participants who experience loss of clinical benefit or unacceptable toxicity during Stage 1 may be eligible …
Effects of NNC0194-0499 alone and in combination with semaglutide, of semaglutide alone, and of cagrilintide alone and in combination with semaglutide on liver damage and alcohol use in people with alcohol-related liver disease
The goal of study 1 and study 2 is to evaluate the effects of ALN-HSD on liver fibrosis and other histologic features of NASH in participants with NASH and F2/F3 fibrosis and risk alleles for HSD17B13. Necessary screening procedures include blood tests, liver stiffness measurement, study-specific genotype criteria, and a …
1 - 10 of 18
- 1
- 2
