Found 8 Eye Disease trials
A listing of Eye Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
Familial lecithin:cholesterol acyl transferase (LCAT) deficiency (FLD) is a rare, hereditary disease with no treatment. It is caused by mutations in the gene for LCAT, an enzyme that is made in the liver and plays a role in the body’s ability to process (“metabolize”) cholesterol. People with FLD have very …
To evaluate the safety and tolerability of OPGx-001 administered via subretinal injection to one eye (treated eye) of participants with LCA5-IRD. The safety and tolerability as assessed by: 1. Number of dose limiting toxicity (DLT) events at the proposed doses 2. Number of procedure-related adverse events (AEs) 3. Number and …
Primary Objectives: 1. To establish the prevalence of neuropathic corneal pain in patients with ocular surface discomfort. 2. To assess the overlap of neuropathic corneal pain with dry eye disease in patients in diseases that are currently thought to be mutually exclusive. 3. To establish the prevalence of subtypes of …
The purpose of this study is to assess the efficacy, safety, pharmacokinetics, and pharmacodynamics of subcutaneous satralizumab, a recombinant, humanized antiinterleukin-6 (IL-6) receptor monoclonal antibody, in participants with moderate-to-severe thyroid eye disease (TED).
The purpose is to evaluate the number of Sjogren's dry eye patients also have decreased sensitivity on the surface of the eye. The study procedures that will be performed during the course of the study involves the following: Corneal Fluorescein staining, Ocular Pain Assessment Scale questionnaire, Corneal Sensitivity test, Schirmer …
Patients with nAMD most commonly receive an anti-VEGF injection into the eye. A "Treat and Extend" method is used to determine how often injections are needed. OCT scans of the eye are used to determine when to give treatment. This study seeks to see how using a Home OCT device …
ATSN-201 is a gene therapy designed to introduce the functional hRS1 gene to photoreceptors in the eye via subretinal admin using a novel rAAV vector, thereby restoring or attenuating the deterioration of vision in patients with XLRS. Subretinally administered AAV vector-mediated gene augmentation therapy has been shown to be safe …
This research involves the study of aging and age-related conditions that can affect memory and thinking in an attempt to improve diagnosis and treatment of Alzheimer’s Disease and related disorders. This study is designed to gain scientific knowledge that may help people in the future. The study aims to recruit …
