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Found 8 Opioid Use Disorder trials

A listing of Opioid Use Disorder medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

 General Screening Protocol for Affected and Unaffected Participants in Studies of Substance Use Disorders

General Screening Protocol for Affected and Unaffected Participants in Studies of Substance Use Disorders

18-64 years
All genders
The goal of this study is to evaluate individuals with and without substance use disorder (SUD) to determine whether it is safe and appropriate for them to participate in a clinical trial, imaging study, or other research protocol that matches the participants’ interests and eligibility. Our goal is to enroll …
 Pilot Study of a Multi-System Analysis of Opioid Receptor Binding

Pilot Study of a Multi-System Analysis of Opioid Receptor Binding

18-50 years
All genders
The purpose of this research is to learn more about mu opioid receptor (MOR) binding in the brain and body. This study will enroll up to 60 adults in three cohorts of up to 20 participants each: Cohort 1: Subjects with a lifetime diagnosis of Opioid Use Disorder (OUD) on …

Opioid and Brain Study

18-60 years
All genders
Have problem with opiates? You may qualify for the study if you are:    - Between 18–60 years old    - In treatment or seeking treatment for opioid use problems    - Willing to complete one MRI scan of the brain  The study will investigate the psychological and brain mechanisms of opioid use disorder. There will be …
 The Whole Health Study: Collaborative Care for OUD and Mental Health Conditions: Randomized Trial

The Whole Health Study: Collaborative Care for OUD and Mental Health Conditions: Randomized Trial

18-99 years
All genders
We are interested in comparing 3 care conditions to determine which condition is best to help people with opioid use disorder (OUD) and mental illness reduce their drug use and improve their psychiatric symptoms. The model we are testing is called collaborative care. This model uses a team-based approach in …

Open label comparison of injectable buprenorphine (CAM2038 Brixadi ) and naltrexone (Vivitrol ) for opioid use disorder

99 years and younger
All genders
Phase 2
Compare brain fMRI response to injectable extended-release buprenorphine (Brixadi, XR-BUP) and naltrexone (XR-NTX, Vivitrol) Our primary outcome combines adherence to treatment and the frequency of illicit opioid use during treatment. The primary outcome is a binary indicator of treatment success: Participants who provide 2 weekly UDS positive for opioids or …
 Emergency Department-Initiated Buprenorphine Validation Network Trial

Emergency Department-Initiated Buprenorphine Validation Network Trial

18-99 years
All genders
Interventional
The purpose of this research study is to compare two versions of the same medication buprenorphine, (commonly known as Suboxone) used to treat opioid use disorder, in patients in the Emergency Department (ED). One form of the medication is a slow-release form of buprenorphine (CAM2038) that lasts for about 7 …
 Addressing Barriers to Engagement with Harm Reduction Services for Opioid Overdose Prevention

Addressing Barriers to Engagement with Harm Reduction Services for Opioid Overdose Prevention

18-100 years
Healthy Volunteer
All genders
Help us understand how to better prevent harm in people who use drugs. If you are over 18, live or work in New York City, and have used drugs in the past 3 months, then you may qualify for a research study on your experiences with harm reduction health services. Eligible …
 Integrating Brain, Neurocognitive, and Computational Tools in Opioid Use Disorder (OUD) to Characterize Executive Function and to Predict Clinical Outcomes

Integrating Brain, Neurocognitive, and Computational Tools in Opioid Use Disorder (OUD) to Characterize Executive Function and to Predict Clinical Outcomes

18-60 years
Healthy Volunteer
All genders
Phase 3
The 5-year K01 Mentored Research Scientist proposal will employ brain, neurocognitive, and computational tools (e.g., machine learning) to understand the impact of opioid-use disorder (OUD) and common co-occurring issues on executive function and clinical outcomes.