Found 15 Inflammation trials
A listing of Inflammation medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
This clinical research trial is being conducted to find out whether the administration of two investigational dMab products (not approved by the US FDA) with an investigational device is safe, tolerated, and can produce enough antibodies in your blood that may indicate the ability to prevent infection of COVID-19.
A research study looking into how ziltivekimab works compared to placebo in people with heart failure and inflammation
This study will determine if ziltivekimab, a monoclonal antibody, can be used to treat people living with heart failure and inflammation. Previous studies showed that ziltivekimab can lower inflammation, which may have a positive effect on heart failure symptoms. The HERMES study will look more into this effect. Also, the …
The purpose of this study is to investigate the presence of tight junctions in gingiva of individuals with periodontitis and peri-implantitis compared to non-inflamed gingiva. We will examine the presence of tight junctions identified by E-cadherin and Zo1 in both periodontitis and peri-implantitis compared to that without inflammation. We will …
The purpose of this study is to see if the study drug ABBV-154 is safe and able to treat subjects with moderately to severely active Crohn's Disease who have an inadequate response to or were intolerant of prior biologics. ABBV-154 is an antibody-drug conjugate, which means it is composed of …
The objectives of the study are:To investigate demographic, clinical, genetic, and environmental factors that contribute to variability in analgesic response to ibuprofen.To compare the inflammatory profile and neutrophil phenotypes between patients who use supplemental opioids and those who do not.To establish a well-phenotyped cohort of subjects, with biobanked samples, that …
Non-steroidal anti-inflammatory drugs (NSAIDs) are commonly used in the treatment of pain and inflammation. Mounting evidence indicates that rectal administration of NSAIDs is also effective in preventing pancreatitis following endoscopic retrograde cholangiopancreatography (ERCP) by an unknown mechanism. Alterations in the salivary and fecal microbiome have been observed in patients with …
The objective of this study is to establish reasonable assurance of safety and effectiveness to support a premarket application (PMA) to the U.S. FDA for the Cortiva Allograft Dermis, a human acellular dermal matrix (ADM), when used on label as an adjunct in two-stage breast reconstruction. The primary safety endpoint …
![Imaging inflammation in individuals with Alcohol Use Disorder: an [18F]NOS study](/media/img/trial_thumbnails/img/siteimg/19_y57mJN5.png)
This is a research study for people ages 18-65 to learn more about how regular alcohol use affects inflammation in the brain and other organs. We will study this using a Positron Emission Tomography (PET/CT) scan using a radioactive imaging drug called [18F]NOS. [18F]NOS is an experimental radioactive molecule used …
This study is an exploratory, two-part, 12-week, Phase 2a study to evaluate the mechanism of action of itepekimab (anti-IL-33-mAb) and its impact on airway inflammation in former and current smokers with COPD.
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