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Found 373 Barrett's Esophagus trials

A listing of Barrett's Esophagus medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

 Effect of study drug IL-4RR576 polymorphism on response to dupilumab in asthma
18-99 years
All genders
Phase 4
The purpose of this study is to learn if the study drug (Dupixent® Dupilumab) helps to control asthma. We are particularly interested in understanding if people who have a certain genetic make-up (genotype) will respond better to this treatment. Participants will take inhaler (Dulera®mometasone/formoterol) about 2-12 weeks. Total study duration …
 Adaptive phase III trial to investigate the efficacy and safety of vilobelimab in the treatment of ulcerative pyoderma gangrenosum
99 years and younger
All genders
This study aims to find out if a new investigational drug, vilobelimab (also called IFX-1) is safe and effective in treating subjects 18 and older diagnosed Ulcerative Pyoderma Gangrenosum. Procedures include blood and urine tests, a physical examination, vital signs, body weight and height, an electrocardiogram (ECG), and full assessment …
18-99 years
Female
Phase 2
This research study is being done to study the safety and toxicity of proton whole pelvis radiation, a type of external beam radiation treatment, for gynecologic cancers after surgery. Currently, for such gynecology cancers, Image- guided Intensity Modulated Radiation Therapy (IG-IMRT) is being done after hysterectomy as the standard treatment. …
 Left Atrial Appendage Exclusion for Prophylactic Stroke Reduction Trial
18-99 years
All genders
The purpose of this study is to evaluate if closing off the left atrial appendage (LAA) of your heart (a small-sack like structure that is part of the upper chamber of the heart) during scheduled heart surgery with a surgical device known as the AtriClip, reduces the risk of a …
18-65 years
All genders
The purpose of this study is to investigate the responses of the brain region known as the subgenual anterior cingulate cortex (sgACC) during transcranial magnetic stimulation (TMS) in individuals with depression. Specifically, investigators aim to determine whether the sgACC is engaged when TMS is delivered to specific targets and if …
 FACT-CRT: Factors Associated with Response to Cardiac Resynchronization Therapy in Heart Failure Patients with Non-LBBB ECG Pattern
18-100 years
All genders
This research study seeks to validate how echocardiogram (echo) data predicts response to cardiac resynchronization therapy (CRT) provided by a CRT device with a defibrillator (CRT-D) in individuals without the heart arrhythmia abnormality left bundle branch block (LBBB). It also aims to identify new variables recorded from electrocardiograms (ECG) or …
 MK-7684A-006: Open-label Phase 3 Study of MK-7684A (Coformulation of Vibostolimab with Pembrolizumab) in Combination with Concurrent Chemoradiotherapy followed by MK-7684A Versus Concurrent Chemoradiotherapy followed by Durvalumab in Participants with Unresectable, Locally Advanced, Stage III NSCLC
18-100 years
All genders
Phase 3
This trial is testing MK-7684A when given in combination with chemotherapy plus radiation therapy (concurrent chemoradiotherapy or cCRT). This trial is for people with stage 3 non-small cell lung cancer (NSCLC). Receiving cCRT is part of the standard treatment for patients with stage 3 NSCLC. MK-7684A, an experimental treatment, is …
 Left vs Left RCT
99 years and younger
All genders
This study aims to test the comparative effectiveness of His or Left bundle branch pacing in relation to patient centered outcomes (quality of life, physical activity, heart failure hospitalization, mortality) and comparative safety in relation to device-related complications. This is for patients with heart failure who are already receiving current …
21-50 years
Accepts healthy volunteer
All genders
The research study is being conducted to better understand the effects of ketosis on brain functioning after three separate 3-day dietary interventions and the acute effects of alcohol during three separate MRI and lab visits after consuming about 4-5 alcohol beverages.
 ACCLAIM-Lp(a) EZEF
99 years and younger
All genders
Phase 3
The purpose of this study is to evaluate the efficacy of lepodisiran in reducing cardiovascular (CV) risk in participants with high lipoprotein(a) who have CV disease or are at risk of a heart attack or stroke. The study aims to learn whether lepodisiran can reduce problems like heart attack or …
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