Found 20 Mitral Valve Regurgitation trials
A listing of Mitral Valve Regurgitation medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
Dynamic Nuclear Polarization-MR Spectroscopic Imaging of Hepatocellular Carcinoma Metabolism to Predict Response Following Locoregional or Systemic Therapy
Phase 2
The research study is being conducted to evaluate a new imaging technique for detecting the response of hepatocellular carcinoma (HCC) to locoregional or systemic therapy. Locoregional therapies or LRT are called Transarterial Chemoembolization or TACE, Transarterial Radioembolization or TARE and Microwave Ablation or MWA. Systemic therapies or ST are therapy …
Changes in the Lymphatic System on the MR Lymphangiography (MRL) In Patients with Liver Cirrhosis
Phase 1
This is an observational study that will compare the differences in lymphatic flow and anatomy of the central lymphatic system on MRL in the liver cirrhosis patients with and without ascites. In the second part of the study, MRL anatomical and flow changes in the central lymphatic system of patients …
Supplement Screening for Breast Cancer with Abbreviated MRI for Black Women with Increased Breast Density
It is well known that black women develop breast cancers which present not only at an earlier age when breasts are denser, but also the cancers tend to be more aggressive subtypes than those found in Caucasian women of a similar age. In addition, the population-based breast cancer mortality for …
MR Spectroscopy Measurement of Tissue NAD+ in Humans
The purpose of this study is to assess repeatability of a magnetic resonance spectroscopy (MRS) technique used to measure NAD+ in the brain and skeletal muscles of different aged individuals. Investigators seek to establish the technique as reliable, when repeated, in each individual.
Pilot study for functional and structural MR Imaging of Endobroncial valve recipients using hyperpoloarized XENON-129
We propose to use gas Magnetic Resonance Imaging (MRI) using the inhaled contrast agent, hyperpolarized (HP) xenon-129, to study the lungs of 20 volunteers who have received or will receive endobronchial valve (EBV) therapy as a treatment for COPD. Since its recent FDA approval, investigators have yet to explicitly assess …
Assessment of the CARILLON Mitral Contour System in Treating Functional Mitral Regurgitation Associated with Heart Failure
Prospective, randomized, blinded clinical trial is to assess the safety and efficacy of the CARILLON Mitral Contour System in treating functional mitral regurgitation associated with heart failure.
Percutaneous or Surgical Repair In Mitral Prolapse And Regurgitation for greater than 65 Year olds
Evaluate the long term effectiveness and safety of mitral valve transcatheter edge to edge repair, TERR, campared with surgical repair in patients with primary, degenerative mitral regurgitation.
Quality Improvement Assessment for Patient-Centered Community Health Worker Intervention
The purpose of the IMPaCT Transitions program is to help low-income general medicine patients who have been cared for at the Hospital of the University of Pennsylvania or Presbyterian Hospital with the transition from hospital to a primary care clinic. The purpose of IMPaCT Home is to help low-SES patients …
Investigating Potential of Personalized Biomarkers in Redefining Treatment Response in Patients with Glioblastoma using Multiparametric MRI and Liquid Biopsy
This study aims to investigate 30 patients with a diagnosis of Glioblastoma to develop a decision support system by incorporating advanced MR imaging, liquid biopsy, and MGMT promoter status to determine with higher accuracy whether tumor changes are true progression or pseudo progression. Analysis of these results will hopefully have …
A Phase 2 Trial Of All-Trans Retinoic Acid (ATRA) Plus PD-1 Inhibition In Recurrent IDH-Mutant Glioma
Phase 2
The purpose of this research study will be to evaluate the safety and effectiveness of two investigational drugs, All-trans retinoic acid (ATRA) and Retifanlimab (anti-PD1 monoclonal antibody), in treating recurrent IDH-mutant gliomas. Objective radiographic response (CR + PR + MR) using Response Assessment in Neuro-Oncology (RANO) criteria by measurable disease …
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