Found 12 Chronic Lymphocytic Leukemia trials
A listing of Chronic Lymphocytic Leukemia medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
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This study investigates the safety and feasibility of using investigational cells called huCART19-IL18 in patients with relapsed or refractory CD19+ cancers. These are cancers where the CD19 protein is present on the surface of malignant cells, such as certain types of lymphoma and leukemia. The purpose is to determine if …
The purpose of this study is to assess the retreatment of chronic lymphocytic leukemia (CLL) using a combination of investigational medications. Participants in this study have previously been treated with a specific therapy involving an anti-CD20 antibody and are now being evaluated for retreatment. The study will look into how …
This study investigates the effects of an investigational medication compared to other treatments chosen by doctors for adults with chronic lymphocytic leukemia (CLL) and moderate to severe heart problems. The study will include people whose heart function is below normal, as measured by a test called left ventricular ejection fraction …
This study investigates the occurrence of irregular heart rhythms in patients with chronic lymphocytic leukemia (CLL) who are treated with Bruton’s Tyrosine Kinase (BTK) inhibitors. The purpose of this study is to use wearable technology to monitor heart rhythms and blood pressure at home, aiming to understand how often patients …
This study investigates the long-term safety and effects of an investigational medication in people with Chronic Lymphocytic Leukemia (CLL), Small Lymphocytic Lymphoma (SLL), or Non-Hodgkin Lymphoma (NHL) who have already received treatment. The purpose of this study is to provide participants from a previous study with the opportunity to continue …
The purpose of this study is to investigate the long-term safety of an investigational medication after participants have completed earlier clinical studies. This study will include individuals from previous studies, called originator studies, and will allow them to continue receiving treatment or follow-up visits. The study will use a master …
This study investigates the use of an investigational treatment, rapcabtagene autoleucel, for different types of blood cancers including chronic lymphocytic leukemia (CLL), small lymphocytic lymphoma (SLL), diffuse large B-cell lymphoma (DLBCL), acute lymphoblastic leukemia (ALL), and high-risk large B-cell lymphoma (HR LBCL).The study consists of two phases. In Phase I, …
This study investigates the safety and efficacy of an investigational medication, surovatamig, administered alone or with other anticancer agents in individuals with mature B-cell malignancies. This study is open-label, meaning both researchers and participants know what treatment is being administered. It includes three substudies, each focusing on different types of …
This study investigates the use of an investigational therapy for patients who have been diagnosed with a condition approved for treatment with this therapy, but whose therapy does not meet commercial release criteria. The purpose is to provide access to this investigational treatment under specific conditions.Participants in this study will …
This study investigates the safety and anti-cancer activity of an investigational medication in adults with advanced B-cell malignancies. These conditions include Chronic Lymphocytic Leukemia (CLL), Small Lymphocytic Lymphoma (SLL), Diffuse Large B-cell Lymphoma (DLBCL), Mantle Cell Lymphoma (MCL), Waldenstrom Macroglobulinemia (WM), Marginal Zone Lymphoma (MZL), Follicular Lymphoma (FL), Primary Central …
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