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Found 7 Chronic Obstructive Lung Disease trials

A listing of Chronic Obstructive Lung Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Pilot, Single Center, Feasibility Study of Cuirass Biphasic Ventilator in Chronic Obstructive Pulmonary Disease Patients

21-79 years
All genders
Phase 1
The research study is being conducted to learn about the work of breathing support that an external breathing support device can provide compared to a person’s baseline ability. The research study is sponsored by RightAir Inc, the makers of the device being investigated, the AIR-AD cuirass ventilator. This study is …

Hyperpolarized xenon functional lung imaging in COPD patients undergoing targeted lung denervation

99 years and younger
All genders
For information regarding study objectives, please see section 8 of the attached protocol. In the context of targeted lung denervation (TLD), we expect the most informative aspect of altered lung function to be related to regional ventilation, as well as possibly the timing of regional inhaled/exhaled gas flow with respect …
 Pilot study for functional and structural MR Imaging of Endobroncial valve recipients using hyperpoloarized XENON-129

Pilot study for functional and structural MR Imaging of Endobroncial valve recipients using hyperpoloarized XENON-129

99 years and younger
All genders
We propose to use gas Magnetic Resonance Imaging (MRI) using the inhaled contrast agent, hyperpolarized (HP) xenon-129, to study the lungs of 20 volunteers who have received or will receive endobronchial valve (EBV) therapy as a treatment for COPD. Since its recent FDA approval, investigators have yet to explicitly assess …

Functional and Structural Assessment of Endobronchial Valve Recipients Using Dynamic Hyperpolarized Xenon-129 MRI

18-90 years
Healthy Volunteer
All genders
The research study is being conducted to determine the effectiveness of using hyperpolarized xenon-129 magnetic resonance imaging (MRI) in diagnosing and predicting treatment outcomes for patients who received endobronchial valve (EBV) therapy to treat chronic obstructive pulmonary disease (COPD). COPD is a disease of the lungs caused most often by …

Aerify III

99 years and younger
All genders
This study is an exploratory, two-part, 12-week, Phase 2a study to evaluate the mechanism of action of itepekimab (anti-IL-33-mAb) and its impact on airway inflammation in former and current smokers with COPD.

OrganOx metra® New Enrollment PAS

99 years and younger
All genders
This is a post approval observational study to gather data on the usage of OrganOx metra to compare the rate of biliary complications after liver transplantation with historical data on livers that have been stored using static cold storage. Subjects will have their donor organ preserved using the study device …
 Study of Daratumumab with Dose-Adjusted EPOCH in Newly Diagnosed Plasmablastic Lymphoma

Study of Daratumumab with Dose-Adjusted EPOCH in Newly Diagnosed Plasmablastic Lymphoma

18-99 years
All genders
Patients with plasmablastic lymphoma are potential participants of this research trial. Patients with a type of B-cell non-Hodgkin lymphoma (NHL) will be invited from Penn Medicine practices. This research study is designed to test the safety of daratumumab, a drug added to the standard lymphoma treatment when given to individuals …